Liver Blood Tests in the Management of Suspected Choledocholithiasis.

Autor: Mongelli F; Department of Surgery, Ospedale Regionale di Lugano, Lugano,Switzerland., Di Giuseppe M; Department of Surgery, Ospedale Regionale di Bellinzona e Valli, Bellinzona,Switzerland., Porcellini I; Department of Surgery, Ospedale Regionale di Bellinzona e Valli, Bellinzona,Switzerland., Proietti F; Department of Surgery, Ospedale Regionale di Lugano, Lugano,Switzerland., Cristaudi A; Department of Surgery, Ospedale Regionale di Lugano, Lugano,Switzerland., Pini R; Department of Surgery, Ospedale Regionale di Bellinzona e Valli, Bellinzona,Switzerland., La Regina D; Department of Surgery, Ospedale Regionale di Bellinzona e Valli, Bellinzona,Switzerland.
Jazyk: angličtina
Zdroj: Laboratory medicine [Lab Med] 2021 Nov 02; Vol. 52 (6), pp. 597-602.
DOI: 10.1093/labmed/lmab042
Abstrakt: Objective: The likelihood of common bile duct (CBD) stones considers liver blood tests (LBTs) if they are markedly altered only. The aim of our study was to find a reliable tool based on LBTs to predict the presence of CBD stones.
Methods: We retrospectively considered all patients who underwent magnetic resonance cholangiopancreatography (MRCP) because of suspected CBD stones from January 2014 to June 2019. Demographic, clinical data, and LBT values were collected and analyzed.
Results: We selected 191 patients, 64 (33.5%) with positive MRCP and 127 (66.5%) with negative MRCP. The analysis showed that our compound LBT-based score had 83.6%, 90.7%, and 90.6% sensitivity, specificity, and negative predictive values, respectively, in determining MRCP results.
Conclusion: We designed a weighted score with high diagnostic power in determining MRCP results that could help in differentiating between candidates for primary cholecystectomy and patients who benefit from preoperative MRCP.
(© American Society for Clinical Pathology, 2021. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
Databáze: MEDLINE
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