PSEUDOPANUVEITIS AS A HARBINGER FOR SYSTEMIC LEUKEMIA RECURRENCE.

Autor:	Altman MT; Casey Eye Institute, Oregon Health & Science University, Portland, OR., Staubach Z; Department of Pathology, Oregon Health & Science University, Portland, OR., Dunlap J; Department of Pathology, Oregon Health & Science University, Portland, OR., Zaki A; Casey Eye Institute, Oregon Health & Science University, Portland, OR., Skalet AH; Casey Eye Institute, Oregon Health & Science University, Portland, OR.; Department of Radiation Medicine, Oregon Health & Science University, Portland, OR; and.; Department of Dermatology, Oregon Health & Science University, Portland, OR., Leonard J; Department of Hematology and Medical Oncology, Oregon Health & Science University, Portland, OR., Lin P; Casey Eye Institute, Oregon Health & Science University, Portland, OR.
Jazyk:	angličtina
Zdroj:	Retinal cases & brief reports [Retin Cases Brief Rep] 2023 Mar 01; Vol. 17 (2), pp. 117-119.
DOI:	10.1097/ICB.0000000000001172
Abstrakt:	Purpose: To describe a patient with a history of pre-B-cell acute lymphoblastic leukemia in remission, who developed recurrent alternating intraocular leukemia manifesting with pseudohypopyon, uveal mass, and serous retinal detachment. In multiple instances, this constellation of ocular findings preceded systemic leukemia recurrence. Method: Case report. Results: A 29-year-old man with a history of pre-B-cell acute lymphoblastic leukemia, in remission after a hematopoietic stem cell transplant, presented with pseudohypopyon, uveal lesions, and serous retinal detachment of the right eye. Comprehensive workup for infectious and inflammatory etiologies was unremarkable, and a bone marrow biopsy revealed systemic recurrence of leukemia. One year later, while again in remission, the patient developed a pseudohypopyon, uveal mass, and serous retinal detachment of the other eye. Repeat bone marrow biopsy showed impending leukemia relapse, which occurred 1 month later. Orbital radiation resulted in complete ocular resolution. Conclusion: The constellation of pseudohypopyon, serous retinal detachment, and uveal mass (pseudopanuveitis) should be recognized as a harbinger for systemic pre-B ALL recurrence.
Databáze:	MEDLINE
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