Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania.

Autor: Nolan C; Center for Global Health, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Reis K; Center for Global Health, Weill Cornell Medicine, New York, NY, USA.; Mwanza Interventional Trials Unit (MITU), Mwanza, Tanzania.; Weill Bugando School of Medicine, Mwanza, Tanzania., Fadhil S; Mwanza Interventional Trials Unit (MITU), Mwanza, Tanzania.; Weill Bugando School of Medicine, Mwanza, Tanzania., Etyang A; KEMRI-Wellcome Trust Research Program, Kilifi, Kenya., Ezeomah C; Center for Global Health, Weill Cornell Medicine, New York, NY, USA.; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA., Kingery JR; Center for Global Health, Weill Cornell Medicine, New York, NY, USA.; Mwanza Interventional Trials Unit (MITU), Mwanza, Tanzania.; Weill Bugando School of Medicine, Mwanza, Tanzania.; Division of General Internal Medicine, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Desderius B; Weill Bugando School of Medicine, Mwanza, Tanzania., Lee MH; Center for Global Health, Weill Cornell Medicine, New York, NY, USA., Kapiga S; Mwanza Interventional Trials Unit (MITU), Mwanza, Tanzania., Peck RN; Center for Global Health, Weill Cornell Medicine, New York, NY, USA.; Mwanza Interventional Trials Unit (MITU), Mwanza, Tanzania.; Weill Bugando School of Medicine, Mwanza, Tanzania.
Jazyk: angličtina
Zdroj: Journal of clinical hypertension (Greenwich, Conn.) [J Clin Hypertens (Greenwich)] 2021 Jul; Vol. 23 (7), pp. 1452-1456. Date of Electronic Publication: 2021 Jun 02.
DOI: 10.1111/jch.14300
Abstrakt: People with HIV (PWH) have a >2-fold greater risk for development of cardiovascular disease (CVD), which may be associated with abnormalities in 24-h ambulatory blood pressure measurement (ABPM) profile. We conducted a nested case-control study of ABPM in 137 PWH and HIV-uninfected controls with normal and high clinic blood pressure (BP) in Tanzania. Nocturnal non-dipping of heart rate (HR) was significantly more common among PWH than HIV-uninfected controls (p = .01). Nocturnal non-dipping of BP was significantly more common in PWH with normal clinic BP (p = .048). Clinical correlates of nocturnal non-dipping were similar in PWH and HIV-uninfected adults and included higher BMI, higher CD4 + cell count, and high C-reactive protein for HR and markers of renal disease for BP. In conclusion, nocturnal non-dipping of both BP and HR was more common in PWH but further research is needed to determine causes and consequences of this difference.
(© 2021 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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