Cyclosporine-Induced Kaposi Sarcoma in a Patient With Ulcerative Colitis.
| Autor: | Clarke LM; Department of Internal Medicine, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, NY., Chawla K; Division of Hepatology and Gastroenterology, The George Washington University Hospital, Washington, DC., Tabbara N; Department of Internal Medicine, UCLA Medical Center, Los Angeles, CA., Szvarca D; Department of Medicine, Johns Hopkins Hospital, Baltimore, MD., Stachura A; Department of General Surgery, Walter Reed National Military Medical Center, Bethesda, MD., Theisen B; Department of Pathology, The George Washington University Hospital, Washington, DC., Chandler M; Division of Hepatology and Gastroenterology, The George Washington University Hospital, Washington, DC., Borum ML; Division of Hepatology and Gastroenterology, The George Washington University Hospital, Washington, DC. |
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| Jazyk: | angličtina |
| Zdroj: | ACG case reports journal [ACG Case Rep J] 2021 May 26; Vol. 8 (5), pp. e00600. Date of Electronic Publication: 2021 May 26 (Print Publication: 2021). |
| DOI: | 10.14309/crj.0000000000000600 |
| Abstrakt: | Kaposi sarcoma (KS) is an angioproliferative neoplasm associated with human herpesvirus-8. Gastrointestinal KS has been well documented in immunosuppressed solid organ transplant patients, with only 26 iatrogenic cases published in patients with inflammatory bowel disease. We report a 24-year-old patient with ulcerative colitis, maintained on cyclosporine for 2 years, who presented with watery, nonbloody diarrhea and weight loss. Colonoscopy revealed human herpesvirus-8-positive hemorrhagic nodules throughout the colon and terminal ileum, with diffuse lymphadenopathy on computed tomography consistent with KS. As gastrointestinal KS may present with symptoms that mimic inflammatory bowel disease, it is critical to maintain suspicion in patients on prolonged immunosuppression to reduce complications. (© 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.) |
| Databáze: | MEDLINE |
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