Association Between Vitamin D and Zinc Levels With Alopecia Areata Phenotypes at a Tertiary Care Center.

Autor:	Alamoudi SM; Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Marghalani SM; Dermatology, King Abdulaziz Medical City, Western Region, Jeddah, SAU., Alajmi RS; Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Aljefri YE; Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Alafif AF; Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2021 Apr 28; Vol. 13 (4), pp. e14738. Date of Electronic Publication: 2021 Apr 28.
DOI:	10.7759/cureus.14738
Abstrakt:	Objectives Alopecia areata (AA) is a common immune-mediated hair disorder that presents in different clinical patterns. This study aims to find the association between vitamin D and zinc levels with AA phenotypes, to determine the common comorbidities in AA patients, and to assess the influence of age, gender, and body mass index (BMI) on AA phenotypes. Methods This is a cross-sectional study conducted at King Abdulaziz Medical City (KAMC) in Jeddah, Saudi Arabia. Data were collected through retrospective chart review of the electronic medical record system (BestCare) and by utilizing a structured data collection sheet. Results A total of 177 patients were clinically diagnosed with AA with a mean age of 28.37 ± 12.68 years. The mean vitamin D level was 49.14 ± 29.09 nmol/L. Zinc levels were reported in only 22 patients, among which, only one patient had deficient levels. The mean zinc level was 9.8 ± 1.5 µmol/L. Patchy alopecia areata (60.45%) was the most common phenotype followed by universalis (9%) and totalis (7%). Hypothyroidism (11.8%) was the most prevalent comorbidity followed by atopic diseases (10.7%), then both diabetes and mood disorders (6.2%). Conclusion Deficient serum vitamin D levels were present in 62.7% of patients with AA. Nevertheless, no statistically significant relation was detected between vitamin D status and patterns of alopecia areata (P=0.108). A limited number of our sample had records of zinc levels with a mean serum of 9.8 ± 1.5 µmol/L and only one patient was found to be deficient. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Alamoudi et al.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu