A Health Surveillance Study of Workers Employed at a Copper Smelter-Effects of Long-Term Exposure to Copper on Lung Function Using Spirometric Data.

Autor: Haase LM; Department of Ramboll Deutschland GmbH, Essen, Germany (Ms Haase, Mr Birk); Ramboll US Consulting, Inc., Amherst, Massachusetts (Dr Bachand); Cardno ChemRisk, Boston, Massachusetts (Dr Mundt)., Birk T, Bachand AM, Mundt KA
Jazyk: angličtina
Zdroj: Journal of occupational and environmental medicine [J Occup Environ Med] 2021 Aug 01; Vol. 63 (8), pp. e480-e489.
DOI: 10.1097/JOM.0000000000002252
Abstrakt: Objective: Significantly lower permissible occupational exposure limits for copper dust are being discussed in Europe and other jurisdictions. However, little data are published on exposures in occupational settings and copper-specific effects in humans. Hence, a health surveillance study was performed among workers employed at a copper smelter between 1972 and 2018.
Methods: Possible effects of long-term exposures to dust containing copper on lung function were assessed. Specifically, declines in forced expiratory volume in 1 second (FEV1) were compared between a copper-exposed and control group. Cumulative copper exposures were derived from historical airborne monitoring data.
Results: FEV1 declines among exposed and control never smokers were similar to a typical age-dependent decline of 29 mL/y.
Conclusion: The study findings indicate that cumulative inhalable copper dust exposure averaging 4.61 mg/m3-years over an exposure duration of ∼22 years is not associated with adverse effects on lung function.
(Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American College of Occupational and Environmental Medicine.)
Databáze: MEDLINE