Nonconvulsive status epilepticus following rotavirus gastroenteritis in two pediatric patients.

Autor: Hirata K; Department of Pediatrics, Soka Municipal Hospital, Saitama, Japan; Department of Pediatrics, Kawaguchi Municipal Medical Center, Saitama, Japan., Sugawara Y; Department of Pediatrics, Soka Municipal Hospital, Saitama, Japan. Electronic address: ysugped@tmd.ac.jp., Hoshino A; Department of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan; Department of Developmental Medical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Takeda S; Department of Pediatrics, Soka Municipal Hospital, Saitama, Japan., Kumada S; Department of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan., Hasegawa T; Department of Pediatrics, Soka Municipal Hospital, Saitama, Japan.
Jazyk: angličtina
Zdroj: Brain & development [Brain Dev] 2021 Oct; Vol. 43 (9), pp. 958-962. Date of Electronic Publication: 2021 May 29.
DOI: 10.1016/j.braindev.2021.05.008
Abstrakt: Background: Nonconvulsive status epilepticus (NCSE) comprises a range of conditions in which prolonged electrographic seizures result in nonconvulsive clinical symptoms. An understanding of NCSE is especially important in emergency care. Among the various causes of NCSE, an infectious etiology has been rarely reported to date.
Case Reports: We report two pediatric cases of rotavirus gastroenteritis complicated by NCSE. In both cases, bilateral rhythmic delta activity (2.5-3 Hz) with occipital predominance fluctuated with the patient's consciousness level. The paroxysmal waves disappeared completely and consciousness immediately and remarkably improved after intravenous midazolam infusion. The patients remained alive 10 and 2 years, respectively, after short-term oral anticonvulsant administration, with no epileptic seizures.
Conclusion: The etiology of NCSE was identical and the clinical presentations were analogous in the two patients. The seizure semiology differed from that in benign convulsion with gastroenteritis. NCSE was considered the prominent cause of neurological symptoms; however, the pathogenic mechanism remains unclear, including the coexistence of acute encephalopathy.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2021 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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