| Autor: |
Roberts MC; Division of Pharmaceutical Outcomes and Policy, University of North Carolina Eshelman School of Pharmacy, 301 Pharmacy Lane, Chapel Hill, NC, 27599, USA., Fohner AE; Department of Epidemiology and Institute of Public Health Genetics, University of Washington, 1959 NE Pacific Ave, Seattle, WA, 98195, USA., Landry L; Harvard Medical School, Harvard T.H. Chan School of Public Health, Brigham and Women's Hospital &The Division of Population Sciences in Dana Farber Cancer Institute, 450 Brookline Ave, Boston, MA, 02215-5450, USA., Olstad DL; Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada., Smit AK; Cancer Epidemiology and Prevention Research, Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, 119-143 Missenden Road, Camperdown, NSW, 2050, Australia., Turbitt E; Discipline of Genetic Counselling, The University of Technology Sydney, 100 Broadway, Ultimo, NSW, 2008, Australia., Allen CG; Department of Behavioral Social and Health Education Sciences, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA, 30322, USA. calle27@emory.edu. |
| Abstrakt: |
Precision public health is a relatively new field that integrates components of precision medicine, such as human genomics research, with public health concepts to help improve population health. Despite interest in advancing precision public health initiatives using human genomics research, current and future opportunities in this emerging field remain largely undescribed. To that end, we provide examples of promising opportunities and current applications of genomics research within precision public health and outline future directions within five major domains of public health: biostatistics, environmental health, epidemiology, health policy and health services, and social and behavioral science. To further extend applications of genomics within precision public health research, three key cross-cutting challenges will need to be addressed: developing policies that implement precision public health initiatives at multiple levels, improving data integration and developing more rigorous methodologies, and incorporating initiatives that address health equity. Realizing the potential to better integrate human genomics within precision public health will require transdisciplinary efforts that leverage the strengths of both precision medicine and public health. |
