Evaluation of a Post-Operative Rehabilitation Program in Patients Undergoing Laparoscopic Colorectal Cancer Surgery: A Pilot Study.

Autor: Nusca SM; PhD Course in 'Translational Medicine and Oncology', Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Parisi A; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', 00135 Rome, Italy., Mercantini P; Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Gasparrini M; Department of General Surgery, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Pitasi FA; Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Lacopo A; Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Colonna V; Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Stella G; Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Cerulli C; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', 00135 Rome, Italy., Grazioli E; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', 00135 Rome, Italy., Tranchita E; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', 00135 Rome, Italy., Santoboni F; Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Latini E; Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Trischitta D; Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Vetrano M; Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Visco V; Department of Clinical and Molecular Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Pavan A; Department of Clinical and Molecular Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy., Vulpiani MC; Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, 'Sapienza' University of Rome, 00189 Rome, Italy.
Jazyk: angličtina
Zdroj: International journal of environmental research and public health [Int J Environ Res Public Health] 2021 May 25; Vol. 18 (11). Date of Electronic Publication: 2021 May 25.
DOI: 10.3390/ijerph18115632
Abstrakt: This pilot study explores the effects of a post-operative physical exercise program on the quality of life (QoL) and functional and nutritional parameters of patients that underwent laparoscopic colorectal cancer surgery, compared to usual care alone. The intervention group (IG) attended a 2-month-long supervised and combined exercise-training program during the post-operative period. Both IG and control group (CG) participated in the QoL, functional, and nutritional assessments before exercise training (T0), 2 months after the beginning of the exercise (end of treatment) (T1), and 2 (T2) and 4 (T3) months from the end of treatment. Eleven patients with colorectal cancer that underwent laparoscopic surgery were enrolled (six intervention; five control). The IG showed significant improvements compared to the CG in "Physical functioning" (PF2) ( p = 0.030), "Cognitive functioning" (CF) ( p = 0.018), and "Fatigue" (FA) ( p = 0.017) of the European Organization for Research and Treatment of Cancer Quality of Life-C30 Questionnaire (EORTC QLQ-C30) at T1; in SMWT ( p = 0.022) at T1; in PF2 ( p = 0.018) and FA ( p = 0.045) of EORTC QLQ-C30 at T2, in phase angle (PhA) of bioelectrical impedance analysis ( p = 0.022) at T3. This pilot study shows that a post-operative, combined, and supervised physical exercise program may have positive effects in improving the QoL, functional capacity, and nutritional status in patients that undergo laparoscopic colorectal cancer surgery.
Databáze: MEDLINE