Pursuing the Diffraction Limit with Nano-LED Scanning Transmission Optical Microscopy.

Autor: Moreno S; Electronic and Biomedical Engineering Department, University of Barcelona, 08028 Barcelona, Spain., Canals J; Electronic and Biomedical Engineering Department, University of Barcelona, 08028 Barcelona, Spain., Moro V; Electronic and Biomedical Engineering Department, University of Barcelona, 08028 Barcelona, Spain., Franch N; Electronic and Biomedical Engineering Department, University of Barcelona, 08028 Barcelona, Spain., Vilà A; Electronic and Biomedical Engineering Department, University of Barcelona, 08028 Barcelona, Spain.; Institute for Nanoscience and Nanotechnology-IN2UB, University of Barcelona, 08028 Barcelona, Spain., Romano-Rodriguez A; Electronic and Biomedical Engineering Department, University of Barcelona, 08028 Barcelona, Spain.; Institute for Nanoscience and Nanotechnology-IN2UB, University of Barcelona, 08028 Barcelona, Spain., Prades JD; Electronic and Biomedical Engineering Department, University of Barcelona, 08028 Barcelona, Spain.; Institute for Nanoscience and Nanotechnology-IN2UB, University of Barcelona, 08028 Barcelona, Spain., Bezshlyakh DD; Institute of Semiconductor Technology, Technische Universität Braunschweig, 38106 Braunschweig, Germany., Waag A; Institute of Semiconductor Technology, Technische Universität Braunschweig, 38106 Braunschweig, Germany., Kluczyk-Korch K; Department of Electronic Engineering, University of Rome 'Tor Vergara', 00133 Roma, Italy.; Faculty of Physics, University of Warsaw, 00-662 Warsaw, Poland., Auf der Maur M; Department of Electronic Engineering, University of Rome 'Tor Vergara', 00133 Roma, Italy., Di Carlo A; Department of Electronic Engineering, University of Rome 'Tor Vergara', 00133 Roma, Italy.; CNR-ISM, 00128 Rome, Italy., Krieger S; Department of Pathology, Medical University of Vienna, 1210 Wien, Austria., Geleff S; Department of Pathology, Medical University of Vienna, 1210 Wien, Austria., Diéguez A; Electronic and Biomedical Engineering Department, University of Barcelona, 08028 Barcelona, Spain.; Institute for Nanoscience and Nanotechnology-IN2UB, University of Barcelona, 08028 Barcelona, Spain.
Jazyk: angličtina
Zdroj: Sensors (Basel, Switzerland) [Sensors (Basel)] 2021 May 11; Vol. 21 (10). Date of Electronic Publication: 2021 May 11.
DOI: 10.3390/s21103305
Abstrakt: Recent research into miniaturized illumination sources has prompted the development of alternative microscopy techniques. Although they are still being explored, emerging nano-light-emitting-diode (nano-LED) technologies show promise in approaching the optical resolution limit in a more feasible manner. This work presents the exploration of their capabilities with two different prototypes. In the first version, a resolution of less than 1 µm was shown thanks to a prototype based on an optically downscaled LED using an LED scanning transmission optical microscopy (STOM) technique. This research demonstrates how this technique can be used to improve STOM images by oversampling the acquisition. The second STOM-based microscope was fabricated with a 200 nm GaN LED. This demonstrates the possibilities for the miniaturization of on-chip-based microscopes.
Databáze: MEDLINE
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