Diagnostic Capacity for Invasive Fungal Infections in the Greek Paediatric Haematology-Oncology Units: Report from the Infection Working Group of the Hellenic Society of Paediatric Haematology-Oncology.

Autor: Markantonatou AM; First Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece., Tragiannidis A; Children & Adolescent Haematology-Oncology Unit, Second Department of Paediatrics, Aristotle University of Thessaloniki, AHEPA Hospital, 53646 Thessaloniki, Greece., Galani V; Paediatric and Adolescent Oncology Clinic, Children's Hospital 'MITERA', 15123 Athens, Greece., Doganis D; Oncology Department, 'P. and A. Kyriakou' Children's Hospital, 11527 Athens, Greece., Antoniadi K; Department of Paediatric Haematology-Oncology, 'Aghia Sophia' Children's Hospital, 11527 Athens, Greece., Tsipou H; Paediatric Haematology-Oncology Unit, First Department of Paediatrics, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, 11527 Athens, Greece., Lambrou M; Department of Paediatric Haematology and Oncology, 'Hippokration' Hospital, 54642 Thessaloniki, Greece., Katzilakis N; Paediatric Haematology Oncology Department, University of Crete, 70013 Heraklion, Greece., Paisiou A; Stem Cell Transplant Unit, 'Aghia Sophia' Children's Hospital, 11527 Athens, Greece., Palabougiouki M; Children & Adolescent Haematology-Oncology Unit, Second Department of Paediatrics, Aristotle University of Thessaloniki, AHEPA Hospital, 53646 Thessaloniki, Greece., Servitzoglou M; Oncology Department, 'P. and A. Kyriakou' Children's Hospital, 11527 Athens, Greece., Papakonstantinou E; Department of Paediatric Haematology and Oncology, 'Hippokration' Hospital, 54642 Thessaloniki, Greece., Peristeri I; Stem Cell Transplant Unit, 'Aghia Sophia' Children's Hospital, 11527 Athens, Greece., Stiakaki E; Paediatric Haematology Oncology Department, University of Crete, 70013 Heraklion, Greece., Kosmidis E; Paediatric and Adolescent Oncology Clinic, Children's Hospital 'MITERA', 15123 Athens, Greece., Polychronopoulou S; Department of Paediatric Haematology-Oncology, 'Aghia Sophia' Children's Hospital, 11527 Athens, Greece., Kattamis A; Paediatric Haematology-Oncology Unit, First Department of Paediatrics, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, 11527 Athens, Greece., Vyzantiadis TA; First Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Jazyk: angličtina
Zdroj: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2021 May 01; Vol. 7 (5). Date of Electronic Publication: 2021 May 01.
DOI: 10.3390/jof7050357
Abstrakt: An audit based on a specific questionnaire was attempted, in order to investigate the mycology laboratory diagnostic capacity for invasive fungal diseases (IFDs) in Greek Paediatric Haematology-Oncology departments/units. The study provided the relevant information for the years 2019 and 2020 and included data from all units, concerning culture-based methods and direct microscopy, phenotypic and molecular identification, sensitivity testing, serology and molecular diagnosis, as well as therapeutic drug monitoring. The target was mostly to reveal the level of laboratory coverage for hospitalised paediatric patients, independently of the possibility of performing the tests in the host hospital, or otherwise to refer the specimens elsewhere. In total, the current study demonstrated that the most important facilities and services regarding the IFD diagnostics for paediatric haematology-oncology patients in Greece are available and relatively easily accessible, with a reasonable turnaround time. Acting as an initial registry for further improvements, the audit can serve as a valuable approach to the actual situation and future perspectives. A national clinical mycology network under the auspices of the relevant scientific societies will probably facilitate collaboration between all the departments (clinical and laboratory) involved in invasive fungal infections and provide an easier approach to any necessary test for any hospitalised patient.
Databáze: MEDLINE