Role of neutrophil-lymphocyte ratio as a predictive factor of glioma tumor grade: A systematic review.

Autor: Gomes Dos Santos A; Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., de Carvalho RF; Hospital Ernesto Dornelles, Porto Alegre, Brazil., de Morais ANLR; Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Silva TM; Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Baylão VMR; Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Azevedo M; Faculdade de Ciências da Universidade Federal do ABC, São Paulo, Brazil., de Oliveira AJM; Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Neurosurgery Department, Clínica Girassol, Luanda, Angola. Electronic address: adilsonvalmont@gmail.com.
Jazyk: angličtina
Zdroj: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2021 Jul; Vol. 163, pp. 103372. Date of Electronic Publication: 2021 May 29.
DOI: 10.1016/j.critrevonc.2021.103372
Abstrakt: Gliomas are the main type of intra-axial primary brain tumors. We performed a systematic review of studies on the neutrophil-to-lymphocyte ratio (NLR) and its role in the prognosis of patients with gliomas. An English-language literature-based search, using the PubMed and Biblioteca Virtual em Saúde databases, was conducted for papers published until May 2, 2020. The quality of the selected articles was stratified using the Newcastle-Ottawa scale's criteria. We found 137 publications for a query string. After applying the inclusion criteria, 13 articles were selected. Seven studies assessed overall survival and found high NLR values associated with poor overall survival. Six studies approached the issue of tumor grading and differential diagnosis and demonstrated that patients with high NLR values were diagnosed with high-grade gliomas. NLR is a low-cost method and an effective prognostic factor associated with tumor grading and OS in patients with gliomas.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: