A case series of parainfectious Guillain-Barré syndrome linked to influenza A (H1N1) virus infection.

Autor: Grisanti SG; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI, Department of Excellence of the Italian Ministry of University and Research), University of Genoa, Genoa, Italy. Electronic address: grisanti.ste@gmail.com., Franciotta D; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI, Department of Excellence of the Italian Ministry of University and Research), University of Genoa, Genoa, Italy; Autoimmunology Laboratory, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Garnero M; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Zuppa A; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI, Department of Excellence of the Italian Ministry of University and Research), University of Genoa, Genoa, Italy., Massa F; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI, Department of Excellence of the Italian Ministry of University and Research), University of Genoa, Genoa, Italy., Mobilia EM; Autoimmunology Laboratory, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Pesce G; Autoimmunology Laboratory, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Schenone A; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI, Department of Excellence of the Italian Ministry of University and Research), University of Genoa, Genoa, Italy., Benedetti L; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Jazyk: angličtina
Zdroj: Journal of neuroimmunology [J Neuroimmunol] 2021 Aug 15; Vol. 357, pp. 577605. Date of Electronic Publication: 2021 May 24.
DOI: 10.1016/j.jneuroim.2021.577605
Abstrakt: Guillain-Barré syndrome (GBS) is an immune-mediated peripheral neuropathy characterized by a typical post-infectious profile. Some post-Zika virus and post-severe acute respiratory syndrome-related coronavirus-2 GBS cases have been reported to occur with very short intervals between the infection and GBS onset. Evaluating 161 GBS patients consecutively admitted to two Italian Regional Hospitals between 2003 and 2019, we found that the only three with an antecedent influenza A (H1N1) virus infection developed GBS within an interval of less than 10 days from the influenza illness. The two of them with a demyelinating subtype promptly recovered without therapy. Overall, the parainfectious cases add heterogeneity to the GBS category, warranting pathogenetic insights.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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