Prediabetes and deprivation: A couple at high risk of diabetes.

Autor: Jaffiol C; National Academy of Medicine, Paris, France., Thomas F; Research department, The Investigations Préventives et Cliniques (IPC) Center, 6, rue La Perouse, 75116 Paris, France. Electronic address: thomas@ipc.asso.fr., Spira A; National Academy of Medicine, Paris, France., Pannier B; Research department, The Investigations Préventives et Cliniques (IPC) Center, 6, rue La Perouse, 75116 Paris, France., Danchin N; Research department, The Investigations Préventives et Cliniques (IPC) Center, 6, rue La Perouse, 75116 Paris, France; University, Paris Descartes, Faculty of Medicine, Paris, France.
Jazyk: angličtina
Zdroj: Revue d'epidemiologie et de sante publique [Rev Epidemiol Sante Publique] 2021 Nov; Vol. 69 (6), pp. 361-365. Date of Electronic Publication: 2021 May 28.
DOI: 10.1016/j.respe.2021.04.139
Abstrakt: Aim: The higher prevalence of diabetes in deprived populations is well documented but little is known about the risk of diabetes associated with deprivation among pre-diabetic subjects. The aim of the study was to evaluate the risk of diabetes in a population of deprived pre-diabetic patients.
Methods: 2743 pre-diabetic subjects identified using the American Diabetes Association (ADA) criteria, 16 to 85 years old, 1656 non-deprived and 1087 deprived, had at least two health check-ups at an interval of 4.95 (2.04) vs 3.20 (1.71) years, P<0.0001, respectively. At the first visit, socioeconomic status was assessed using the EPICES score to differentiate deprived and non-deprived subjects.
Results: At the second visit, the prevalence of overt diabetes was 9.5% among deprived vs 5.1% in the non-deprived group (P<0.001). After adjustment on confounding factors, deprivation was found independently associated with occurrence of diabetes [1.70 (1.15-2.51), P=0.01]. Beyond social deprivation, Fasting Plasma Glucose and waist circumference were the main independent predictors of new-onset diabetes.
Conclusion: After 4 years of follow-up, among subjects with prediabetes, prevalence of diabetes was twice as high among deprived compared with non-deprived subjects. Deprived populations with pre-diabetes may require specific public health approaches to avoid the occurrence of overt diabetes.
(Copyright © 2021 Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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