The structure and prebiotic activity of arabinogalactan from Ferula Kuhistаnica.

Autor: Rakhmanberdyeva RK; Department of Chemistry of High Molecular Plant Substances, Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, 77, M. Ulugbek Str., 100170, Tashkent, Uzbekistan. Electronic address: rakhmanberdieva@mail.ru., Shashkov AS; N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, B-334, Leninsky Prosp., 47, Moscow, Russia. Electronic address: shash@ioc.ac.ru., Bobakulov KM; Department of Physical Methods of Research, Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, 77, M. Ulugbek Str., 100170, Tashkent, Uzbekistan; Tashkent Institute of Irrigation and Agricultural Mechanization Engineers. 39, Kori Niyoziy Str., 100000, Tashkent, Uzbekistan. Electronic address: khayrulla@rambler.ru., Azizov DZ; Department of Chemistry of High Molecular Plant Substances, Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, 77, M. Ulugbek Str., 100170, Tashkent, Uzbekistan., Malikova MK; Department of Chemistry of High Molecular Plant Substances, Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, 77, M. Ulugbek Str., 100170, Tashkent, Uzbekistan., Ogay DK; Institute of Microbiology, Academy of Sciences of the Republic of Uzbekistan, 7B, A. Kadyri Str., 100128, Tashkent, Uzbekistan.
Jazyk: angličtina
Zdroj: Carbohydrate research [Carbohydr Res] 2021 Jul; Vol. 505, pp. 108342. Date of Electronic Publication: 2021 May 24.
DOI: 10.1016/j.carres.2021.108342
Abstrakt: Acidic arabinogalactan with molecular weight 36 kDa was isolated from the aerial part of Ferula kuhistаnica, the monosaccharide composition of which is represented by galactose and arabinose in a ratio of 3.6:1. The chemical and spectral methods revealed a main polymer chain consisting of (1 → 6) β-galactopyranose residues, where in position of C-3 were the residues of α-arabinofuranose and its 1,5-linked oligomers, as well as β-GlcpA-4-OMe-(1 → 6)-β-Galp-(1→ fragments. In addition, a small part of the main chain carries monosaccharide residues of β-Galp-(1→ in position C-2. The effect of arabinogalactan on the growth of an associative culture of bifidobacteria and some mono-strains of lactobacilli was studied and it was shown that it exhibits more effective prebiotic activity.
(Copyright © 2021 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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