Bovine Immune Responses to Moraxella bovis and Moraxella bovoculi Following Vaccination and Natural or Experimental Infections.
| Autor: | Angelos JA; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA, USA. Electronic address: jaangelos@ucdavis.edu., Elizalde P; School of Public Health, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Griebel P; School of Public Health, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; VIDO-Intervac, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. |
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| Jazyk: | angličtina |
| Zdroj: | The Veterinary clinics of North America. Food animal practice [Vet Clin North Am Food Anim Pract] 2021 Jul; Vol. 37 (2), pp. 253-266. |
| DOI: | 10.1016/j.cvfa.2021.03.002 |
| Abstrakt: | Studies have sought to develop effective vaccines against infectious bovine keratoconjunctivitis (IBK). Most research has focused on parenterally administered vaccines against Moraxella bovis antigens; however, researchers have also included Moraxella bovoculi antigens in vaccines to prevent IBK. Critical knowledge gaps remain as to which Moraxella spp antigens might be completely protective, and whether systemic, mucosal, or both types of immune responses are required for protection against IBK associated with Moraxella spp. Immune responses to commensal Moraxella spp residing in the upper respiratory tract and eye have not been analyzed to determine if these responses control colonization or contribute to IBK. Competing Interests: Disclosure The authors have nothing to disclose. (Copyright © 2021 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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