Supplemental Oxygen and Surgical Site Infection in Colorectal Surgery: A Systematic Review and Meta-analysis.

Autor: Shaffer SK; is a full time assistant professor at Texas Wesleyan University Graduate Programs of Nurse Anesthesia. Email: sshaffer@txwes.edu., Tubog TD; is the assistant program director at Texas Wesleyan University Graduate Programs of Nurse Anesthesia., Kane TD; is the program director at Texas Wesleyan University Graduate Programs of Nurse Anesthesia., Stortroen NE; is the director of Clinical Education at Texas Wesleyan University Graduate Programs of Nurse Anesthesia.
Jazyk: angličtina
Zdroj: AANA journal [AANA J] 2021 Jun; Vol. 89 (3), pp. 245-253.
Abstrakt: Surgical site infection (SSI) is a common preventable iatrogenic infection following surgery with an approximated overall occurrence of 2-4%. Despite numerous studies, controversies still exist regarding the efficacy, safety, and cost effectiveness of strategies to decrease SSI. The World Health Organization issued recommendations for the prevention of SSIs including oxygenation with 80% fraction of inspired oxygen (FiO 2 ). The primary outcome of our systematic review and metaanalysis was the effect of high inspired FiO 2 related to SSI in the colorectal surgery population. Secondary outcomes included incidence of anastomotic leaks and length of hospital stay. Eleven trials consisting of 8245 were included in the analysis. We found moderate quality of evidence that 80% FiO2 was not effective in reducing SSI (RR, 0.91; 95% CI, 0.74 to 1.13; P = .41) anastomotic leaks (RR, 0.75; 95% CI, 0.53 to 1.06; P = 0.10). Conversely, we found low quality evidence of no effect on length of stay measured in days (MD, 0.39; 95% CI -0.59 to 1.36; P = 0.44). Although additional studies are required to decrease heterogeneity of the studies, the current review showed high FiO 2 does not decrease the incidence of SSI in the colorectal surgery population.
Competing Interests: Scott Shaffer, DNAP, CRNA, has declared no financial relationships with any commercial entity related to the content of this article. Tito Tubog, DNAP, CRNA, has declared no financial relationships with any commercial entity related to the content of this article. Terri Kane DNAP, CRNA, has declared no financial relationships with any commercial entity related to the content of this article. Nathan Stortroen, DNP, CRNA, has declared no financial relationships with any commercial entity related to the content of this article. The authors did not disclose off-label use within the article. Disclosure statements are available for review upon request.
(Copyright © by the American Association of Nurse Anesthetists.)
Databáze: MEDLINE
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