Cardiac computed tomography-derived extracellular volume fraction in late anthracycline-induced cardiotoxicity.

Autor:	Egashira K; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Sueta D; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Tomiguchi M; Breast and Endocrine Surgery, Graduate School of Medical Sciences, Kumamoto, Japan., Kidoh M; Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto, Japan., Oda S; Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto, Japan., Usuku H; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan.; Department of Laboratory Medicine, Kumamoto University Hospital, Kumamoto, Japan., Hidaka K; Breast and Endocrine Surgery, Graduate School of Medical Sciences, Kumamoto, Japan., Goto-Yamaguchi L; Breast and Endocrine Surgery, Graduate School of Medical Sciences, Kumamoto, Japan., Sueta A; Breast and Endocrine Surgery, Graduate School of Medical Sciences, Kumamoto, Japan., Komorita T; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Takae M; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Oike F; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Fujisue K; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Yamamoto E; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Hanatani S; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Takashio S; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Arima Y; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Araki S; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Kaikita K; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan., Matsushita K; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan.; Division of Advanced Cardiovascular Therapeutics, Kumamoto University Hospital, Kumamoto, Japan., Yamamoto Y; Breast and Endocrine Surgery, Graduate School of Medical Sciences, Kumamoto, Japan., Hirai T; Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto, Japan., Tsujita K; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Graduate School of Medical Sciences, Kumamoto, Japan.
Jazyk:	angličtina
Zdroj:	International journal of cardiology. Heart & vasculature [Int J Cardiol Heart Vasc] 2021 May 18; Vol. 34, pp. 100797. Date of Electronic Publication: 2021 May 18 (Print Publication: 2021).
DOI:	10.1016/j.ijcha.2021.100797
Abstrakt:	Cardiotoxicity in the late phase after anthracycline drugs administration remains to be defined. Of the 44 patients who received anthracycline treatment, 7 were found to have cancer therapeutics-related cardiac dysfunction (CTRCD). The global longitudinal strain determined by echocardiography and myocardial extracellular volume fraction (ECV) determined by cardiac computed tomography (CCT) of the CTRCD(+) group were significantly higher than those of the control group and CTRCD(-) group, whereas there were no significant differences between the control and CTRCD(-) groups. Our findings indicated that CCT may be a tool comparable to echocardiography, indicating the effective evaluation of CTRCD by CCT. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2021 The Author(s).)
Databáze:	MEDLINE
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