68Ga-DOTATATE PET/CT Distinguishes Neuroendocrine Tumor Mesenteric Lymph Node Metastasis From an Extensive IgG4-Positive Fibrosis Surrounding It.
| Autor: | Ahmadi Bidakhvidi N; From the Departments of Nuclear Medicine., Cuyle PJ, Sagaert X; Department of Anatomical Pathology, University Hospitals Leuven, Leuven., Ballaux F; Department of Anatomical Pathology, Imelda Hospital, Bonheiden, Belgium., Deroose CM; From the Departments of Nuclear Medicine. |
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| Jazyk: | angličtina |
| Zdroj: | Clinical nuclear medicine [Clin Nucl Med] 2021 Oct 01; Vol. 46 (10), pp. e510-e512. |
| DOI: | 10.1097/RLU.0000000000003722 |
| Abstrakt: | Abstract: A 56-year-old woman presented with right iliac fossa pain. Abdominal CT showed a mesenteric mass in the right iliac fossa, adjacent to the vena cava inferior and right ureter. Biopsy of the mass revealed a well-differentiated neuroendocrine tumor. 68Ga-DOTATATE PET/CT showed strong somatostatin receptor expression only within in a small, central area of this mesenteric mass, with faint 68Ga-DOTATATE uptake in the majority of this mesenteric mass. Pathology revealed an IgG4-positive storiform fibrosis surrounding a mesenteric adenopathy. 68Ga-DOTATATE PET/CT discriminates between neuroendocrine tumor lymph node metastases and fibrosis, hereby avoiding potential sampling error of tumor biopsies and guiding surgical approach. Competing Interests: Conflicts of interest and sources of funding: none declared. (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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