A National Survey of Practice Patterns for Accepting Living Kidney Donors With Prior COVID-19.

Autor:	Jan MY; Indiana University School of Medicine, Indianapolis, Indiana, USA., Jawed AT; Wayne State University, Detroit, Michigan, USA., Barros N; Indiana University School of Medicine, Indianapolis, Indiana, USA., Adebiyi O; Indiana University School of Medicine, Indianapolis, Indiana, USA., Diez A; The Ohio State University, Columbus, Ohio, USA., Fridell JA; Indiana University School of Medicine, Indianapolis, Indiana, USA., Goggins WC; Indiana University School of Medicine, Indianapolis, Indiana, USA., Yaqub MS; Indiana University School of Medicine, Indianapolis, Indiana, USA., Anderson MD; Indiana University School of Medicine, Indianapolis, Indiana, USA., Mujtaba MA; University of Texas Medical Branch UTMB Galveston, Galveston, Texas, USA., Taber TE; Indiana University School of Medicine, Indianapolis, Indiana, USA., Mishler DP; Indiana University School of Medicine, Indianapolis, Indiana, USA., Kumar V; University of Alabama, Birmingham, Alabama, USA., Lentine KL; St. Louis University, St. Louis, Missouri, USA., Sharfuddin AA; Indiana University School of Medicine, Indianapolis, Indiana, USA.
Jazyk:	angličtina
Zdroj:	Kidney international reports [Kidney Int Rep] 2021 Aug; Vol. 6 (8), pp. 2066-2074. Date of Electronic Publication: 2021 May 15.
DOI:	10.1016/j.ekir.2021.05.003
Abstrakt:	Introduction: A critical question facing transplant programs is whether, when, and how to safely accept living kidney donors (LKDs) who have recovered from COVID-19 infection. The purpose of the study is to understand current practices related to accepting these LKDs. Methods: We surveyed US transplant programs from 3 September through 3 November 2020. Center level and participant level responses were analyzed. Results: A total of 174 respondents from 115 unique centers responded, representing 59% of US LKD programs and 72.4% of 2019 and 72.5% of 2020 LKD volume (Organ Procurement and Transplantation Network-OPTN 2021). In all, 48.6% of responding centers had received inquiries from such LKDs, whereas 44.3% were currently evaluating. A total of 98 donors were in the evaluation phase, whereas 27.8% centers had approved 42 such donors to proceed with donation. A total of 50.8% of participants preferred to wait >3 months, and 91% would wait at least 1 month from onset of infection to LD surgery. The most common reason to exclude LDs was evidence of COVID-19-related AKI (59.8%) even if resolved, followed by COVID-19-related pneumonia (28.7%) and hospitalization (21.3%). The most common concern in accepting such donors was kidney health postdonation (59.2%), followed by risk of transmission to the recipient (55.7%), donor perioperative pulmonary risk (41.4%), and donor pulmonary risk in the future (29.9%). Conclusion: Practice patterns for acceptance of COVID-19-recovered LKDs showed considerable variability. Ongoing research and consensus building are needed to guide optimal practices to ensure safety of accepting such donors. Long-term close follow-up of such donors is warranted. (© 2021 International Society of Nephrology. Published by Elsevier Inc.)
Databáze:	MEDLINE
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