Enhanced conversion of biomass to furfurylamine with high productivity by tandem catalysis with sulfonated perlite and ω-transaminase whole-cell biocatalyst.

Autor: Di JH; National-Local Joint Engineering Research Center of Biomass Refining and High-Quality Utilization, School of Pharmacy, Changzhou University, Changzhou, People's Republic of China., Gong L; National-Local Joint Engineering Research Center of Biomass Refining and High-Quality Utilization, School of Pharmacy, Changzhou University, Changzhou, People's Republic of China., Yang D; National-Local Joint Engineering Research Center of Biomass Refining and High-Quality Utilization, School of Pharmacy, Changzhou University, Changzhou, People's Republic of China., He YC; National-Local Joint Engineering Research Center of Biomass Refining and High-Quality Utilization, School of Pharmacy, Changzhou University, Changzhou, People's Republic of China; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, People's Republic of China; Jiangsu Key Laboratory for Biomass-based Energy and Enzyme Technology, Huaiyin Normal University, Huaian, People's Republic of China. Electronic address: heyucai2001@163.com., Tang ZY; National-Local Joint Engineering Research Center of Biomass Refining and High-Quality Utilization, School of Pharmacy, Changzhou University, Changzhou, People's Republic of China., Ma CL; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, People's Republic of China. Electronic address: macuiluan@163.com.
Jazyk: angličtina
Zdroj: Journal of biotechnology [J Biotechnol] 2021 Jun 20; Vol. 334, pp. 26-34. Date of Electronic Publication: 2021 May 18.
DOI: 10.1016/j.jbiotec.2021.05.003
Abstrakt: Production of bio-based chemicals from renewable bioresource is a key driver for moving towards sustainable industry. Furfurylamine is known as an important furfural-upgrading product in organic synthesis, as well as monolithic synthetic pharmaceuticals, fibers, additives and polymers. In one-pot manner, biomass was tandemly catalyzed to furfurylamine with sulfonated Sn-PL catalyst and recombinant ω-transaminase biocatalyst. Sn-PL (2.4 wt%) catalyzed bamboo shoot shell, corncob and rice straw (75.0 g/L) to 76.5-113.0 mM furfural at 44.7-58.5 % yield in γ-valerolactone-water (2:8, v:v) at 170 ℃. The obtained biomass slurries containing furfural were biotransformed to furfurylamine at high yield (0.39-0.42 g furfurylamine/g xylan in biomass) with ω-transaminase biocatalyst using isopropylamine (3.0 mol isopropylamine/mol furfural) as amine donor at 35 ℃. Such a chemoenzymatic one-pot process combined the advantages of both solid acids and whole-cells catalysts, which provided an efficient and sustainable approach for preparing an important bio-based furan chemical furfurylamine.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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