Child Neurology: RNA Sequencing for the Diagnosis of Lissencephaly.

Autor: Qashqari H; From the Division of Neurology, Department of Pediatrics (H.Q., H.G., K.A., J.J.D.), Centre for Computational Medicine (A.R., M.B.), and Program of Genetic and Genome Biology (H.G., K.A., M.M.G.S., M.B., J.J.D.), the Hospital for Sick Children, and Department of Pediatrics (J.J.D.), Department of Molecular Genetics (J.J.D.), and Research Department of Computer Science (M.B.), University of Toronto, Canada; Department of Biostatistics (S.N.), Harvard Chan School of Public Health, Boston, MA; Department of Human Genetics (S.D.), University of Chicago, IL; and Techna Institute (M.B.), University Health Network, Toronto, Canada., Ramani A; From the Division of Neurology, Department of Pediatrics (H.Q., H.G., K.A., J.J.D.), Centre for Computational Medicine (A.R., M.B.), and Program of Genetic and Genome Biology (H.G., K.A., M.M.G.S., M.B., J.J.D.), the Hospital for Sick Children, and Department of Pediatrics (J.J.D.), Department of Molecular Genetics (J.J.D.), and Research Department of Computer Science (M.B.), University of Toronto, Canada; Department of Biostatistics (S.N.), Harvard Chan School of Public Health, Boston, MA; Department of Human Genetics (S.D.), University of Chicago, IL; and Techna Institute (M.B.), University Health Network, Toronto, Canada., Gonorazky H; From the Division of Neurology, Department of Pediatrics (H.Q., H.G., K.A., J.J.D.), Centre for Computational Medicine (A.R., M.B.), and Program of Genetic and Genome Biology (H.G., K.A., M.M.G.S., M.B., J.J.D.), the Hospital for Sick Children, and Department of Pediatrics (J.J.D.), Department of Molecular Genetics (J.J.D.), and Research Department of Computer Science (M.B.), University of Toronto, Canada; Department of Biostatistics (S.N.), Harvard Chan School of Public Health, Boston, MA; Department of Human Genetics (S.D.), University of Chicago, IL; and Techna Institute (M.B.), University Health Network, Toronto, Canada., Amburgey K; From the Division of Neurology, Department of Pediatrics (H.Q., H.G., K.A., J.J.D.), Centre for Computational Medicine (A.R., M.B.), and Program of Genetic and Genome Biology (H.G., K.A., M.M.G.S., M.B., J.J.D.), the Hospital for Sick Children, and Department of Pediatrics (J.J.D.), Department of Molecular Genetics (J.J.D.), and Research Department of Computer Science (M.B.), University of Toronto, Canada; Department of Biostatistics (S.N.), Harvard Chan School of Public Health, Boston, MA; Department of Human Genetics (S.D.), University of Chicago, IL; and Techna Institute (M.B.), University Health Network, Toronto, Canada., Ghahramani Seno MM; From the Division of Neurology, Department of Pediatrics (H.Q., H.G., K.A., J.J.D.), Centre for Computational Medicine (A.R., M.B.), and Program of Genetic and Genome Biology (H.G., K.A., M.M.G.S., M.B., J.J.D.), the Hospital for Sick Children, and Department of Pediatrics (J.J.D.), Department of Molecular Genetics (J.J.D.), and Research Department of Computer Science (M.B.), University of Toronto, Canada; Department of Biostatistics (S.N.), Harvard Chan School of Public Health, Boston, MA; Department of Human Genetics (S.D.), University of Chicago, IL; and Techna Institute (M.B.), University Health Network, Toronto, Canada., Brudno M; From the Division of Neurology, Department of Pediatrics (H.Q., H.G., K.A., J.J.D.), Centre for Computational Medicine (A.R., M.B.), and Program of Genetic and Genome Biology (H.G., K.A., M.M.G.S., M.B., J.J.D.), the Hospital for Sick Children, and Department of Pediatrics (J.J.D.), Department of Molecular Genetics (J.J.D.), and Research Department of Computer Science (M.B.), University of Toronto, Canada; Department of Biostatistics (S.N.), Harvard Chan School of Public Health, Boston, MA; Department of Human Genetics (S.D.), University of Chicago, IL; and Techna Institute (M.B.), University Health Network, Toronto, Canada., Naumenko S; From the Division of Neurology, Department of Pediatrics (H.Q., H.G., K.A., J.J.D.), Centre for Computational Medicine (A.R., M.B.), and Program of Genetic and Genome Biology (H.G., K.A., M.M.G.S., M.B., J.J.D.), the Hospital for Sick Children, and Department of Pediatrics (J.J.D.), Department of Molecular Genetics (J.J.D.), and Research Department of Computer Science (M.B.), University of Toronto, Canada; Department of Biostatistics (S.N.), Harvard Chan School of Public Health, Boston, MA; Department of Human Genetics (S.D.), University of Chicago, IL; and Techna Institute (M.B.), University Health Network, Toronto, Canada., Das S; From the Division of Neurology, Department of Pediatrics (H.Q., H.G., K.A., J.J.D.), Centre for Computational Medicine (A.R., M.B.), and Program of Genetic and Genome Biology (H.G., K.A., M.M.G.S., M.B., J.J.D.), the Hospital for Sick Children, and Department of Pediatrics (J.J.D.), Department of Molecular Genetics (J.J.D.), and Research Department of Computer Science (M.B.), University of Toronto, Canada; Department of Biostatistics (S.N.), Harvard Chan School of Public Health, Boston, MA; Department of Human Genetics (S.D.), University of Chicago, IL; and Techna Institute (M.B.), University Health Network, Toronto, Canada., Dowling JJ; From the Division of Neurology, Department of Pediatrics (H.Q., H.G., K.A., J.J.D.), Centre for Computational Medicine (A.R., M.B.), and Program of Genetic and Genome Biology (H.G., K.A., M.M.G.S., M.B., J.J.D.), the Hospital for Sick Children, and Department of Pediatrics (J.J.D.), Department of Molecular Genetics (J.J.D.), and Research Department of Computer Science (M.B.), University of Toronto, Canada; Department of Biostatistics (S.N.), Harvard Chan School of Public Health, Boston, MA; Department of Human Genetics (S.D.), University of Chicago, IL; and Techna Institute (M.B.), University Health Network, Toronto, Canada. James.Dowling@sickkids.ca.
Jazyk: angličtina
Zdroj: Neurology [Neurology] 2021 Sep 20; Vol. 97 (12), pp. e1253-e1256. Date of Electronic Publication: 2021 Sep 20.
DOI: 10.1212/WNL.0000000000012265
Databáze: MEDLINE