Delivery of Inhaled Nitric Oxide During MRI to Ventilated Neonates and Infants.

Autor: Carter BG; Clinical Technology Service, Neonatal and Paediatric Intensive Care Units, Royal Children's Hospital, Parkville, Victoria, Australia. bradley.carter@rch.org.au., Swain R; Clinical Technology Service, Neonatal and Paediatric Intensive Care Units, Royal Children's Hospital, Parkville, Victoria, Australia., Hislop J; Clinical Technology Service, Neonatal and Paediatric Intensive Care Units, Royal Children's Hospital, Parkville, Victoria, Australia., Escudie M; Clinical Technology Service, Neonatal and Paediatric Intensive Care Units, Royal Children's Hospital, Parkville, Victoria, Australia., H Williams R; Clinical Technology Service, Neonatal and Paediatric Intensive Care Units, Royal Children's Hospital, Parkville, Victoria, Australia.
Jazyk: angličtina
Zdroj: Respiratory care [Respir Care] 2021 Aug; Vol. 66 (8), pp. 1254-1262. Date of Electronic Publication: 2021 May 18.
DOI: 10.4187/respcare.08408
Abstrakt: Background: Many pediatric and neonatal ICU patients receive nitric oxide (NO), with some also requiring magnetic resonance imaging (MRI) scans. MRI-compatible NO delivery devices are not always available. We describe and bench test a method of delivering NO during MRI using standard equipment in which a NO delivery device was positioned in the MRI control room with the NO blender component connected to oxygen and set to 80 ppm and delivering flow via 12 m of tubing to a MRI-compatible ventilator, set up inside the MRI scanner magnet room.
Methods: For our bench test, the ventilator was set up normally and connected to an infant test lung to simulate several patients of differing weight (ie, 4 kg, 10 kg, 20 kg). The NO blender delivered flows of 2-10 L/min to the ventilator to achieve a range of NO and oxygen concentrations monitored via extended tubing. The measured values were compared to calculated values.
Results: A range of NO concentrations (12-41 ppm) and F IO 2 values (0.67-0.97) were achieved during the bench testing. The additional flow increased delivered peak inspiratory pressure and PEEP by 1-5 cm H 2 O. Calculated values were within acceptable ranges and were used to create a lookup table.
Conclusions: In clinical use, this system can safely generate a range of NO flows of 15-42 ppm with an accompanying F IO 2 range of 0.34-0.98.
Competing Interests: The authors have disclosed no conflicts of interest.
(Copyright © 2021 by Daedalus Enterprises.)
Databáze: MEDLINE
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