Establishing Sickle Cell Disease Stroke Prevention Teams in Africa is Feasible: Program Evaluation Using the RE-AIM Framework.

Autor:	Ghafuri DL; Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt-Meharry Center of Excellence in Sickle Cell Disease., Abdullahi SU; Departments of Pediatrics., Dambatta AH; Radiology., Galadanci J; Department of Computer Science, Bayero University., Tabari MA; Departments of Radiology., Bello-Manga H; Hematology and Blood Transfusion., Idris N; Departments of Radiology., Inuwa H; Departments of Pediatrics., Tijjani A; Departments of Pediatrics., Suleiman AA; Departments of Radiology., Jibir BW; Pediatrics, Murtala Mohammed Specialist Hospital., Gambo S; Pediatrics, Murtala Mohammed Specialist Hospital., Gambo AI; Pediatrics, Murtala Mohammed Specialist Hospital., Khalifa Y; Department of Administration, Aminu Kano Teaching Hospital, Kano., Haliru L; Department of Pediatrics, Barau Dikko Teaching Hospital/Kaduna State University, Kaduna, Nigeria., Abdulrasheed S; Department of Pediatrics, Barau Dikko Teaching Hospital/Kaduna State University, Kaduna, Nigeria., Zakari MA; Histopathology, Bayero University/Aminu Kano Teaching Hospital., Greene BC; Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt-Meharry Center of Excellence in Sickle Cell Disease., Trevathan E; Department of Neurology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN., Jordan LC; Department of Pediatrics, Division of Pediatric Neurology., Aliyu MH; Health Policy, Vanderbilt Institute for Global Health, Vanderbilt University Medical Center., Baumann AA; Brown School of Social Work, Washington University of St. Louis, St. Louis, MO., DeBaun MR; Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt-Meharry Center of Excellence in Sickle Cell Disease.
Jazyk:	angličtina
Zdroj:	Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2022 Jan 01; Vol. 44 (1), pp. e56-e61.
DOI:	10.1097/MPH.0000000000002179
Abstrakt:	We used the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework to evaluate a Stroke Prevention Team's readiness to prevent strokes in children with sickle cell anemia living in northern Nigeria. The NIH sponsored Stroke Prevention Trial in Nigeria included a goal of a sustainable stroke prevention program. The program's 1-year reach for transcranial Doppler screening was 14.7% (4710/32,000) of which 6.0% (281/4710) had abnormal velocities (≥200 cm/s). All participants with abnormal transcranial Doppler velocities were started on hydroxyurea (effectiveness). The leaders of all 5 hospitals agreed to adopt the program. After 1 year, program-implementation and maintenance rates were 100%, demonstrating the program's feasibility and short-term sustainability. Competing Interests: M.R.D.: had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. M.R.D.: designed the study. S.U.A. and M.A.T.: provided the TCD training. A.H.D., H.B.-M., H.I., A.T., A.A.S., B.W.J., S.G., Y.K., L.H., S.A., M.A.Z., and N.I.: administered the TCD screening. E.T. and L.J.: verified the neurological examinations. A.I.G., F.M.U., M.A.T., A.I.G., S.U.A., B.C.G., J.G., and D.L.G.: collected the data. D.L.G. and M.R.: performed the analyses. M.R.D., S.A., D.L.G., A.A.B., M.R.D.: interpreted the results. D.L.G., A.A.B., L.C.J., E.T., M.H.A., and M.R.D.: wrote the manuscript. Before submission, all authors reviewed the manuscript.The authors declare no conflict of interest. (Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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