Validating the revised Symptom Impact Questionnaire with a proposed fibromyalgia phenotype using experimentally-induced pain and patient self-reports.

Autor:	Friend R; Fibromyalgia Research Unit, Oregon Health & Science University, Portland, OR, and Department of Psychology, College of Arts & Sciences, Stony Brook University, Stony Brook, NY, USA. ronald.friend@stonybrook.edu., Bennett RM; Fibromyalgia Research Unit, Oregon Health & Science University, Portland, OR, and School of Medicine, Oregon Health & Science University, Portland, OR, USA., Aebischer JH; School of Nursing, Oregon Health & Science University, Portland, OR and Central City Concern, Portland, OR, USA., St John AW; School of Medicine, Anaesthesiology & Perioperative Medicine, Oregon Health & Science University, Portland, OR, USA., Jones KD; Fibromyalgia Research Unit, Oregon Health & Science University, Portland, OR, and School of Nursing, Linfield University and Professor, OHSU School of Medicine, Neurology-Research Affiliate, Oregon Health & Science University Portland, OR, USA.
Jazyk:	angličtina
Zdroj:	Clinical and experimental rheumatology [Clin Exp Rheumatol] 2021 May-Jun; Vol. 39 Suppl 130 (3), pp. 137-143. Date of Electronic Publication: 2021 May 14.
DOI:	10.55563/clinexprheumatol/klmx7e
Abstrakt:	Objectives: The Symptom Impact Questionnaire (SIQR), now used for over a decade, has strong psychometric properties based on patients' subjective questionnaire data and correlations with other general measures of severity. However, the construct validity of the SIQR in assessing the central features of fibromyalgia (FM) has not been tested specifically with more objective measures. This study examined the construct validity of the SIQR using clinical examination of prominent features of FM, as well as patient questionnaire data. Methods: We determined if SIQR severity groups (low, moderate, high severity) in 158 chronic pain patients (50 FM, 108 Pain/No FM) predicted four central features of FM tenderness and pain: digital palpation tenderness, blood pressure cuff evoked pain, widespread pain locations, and a persistent deep ache question. Results: Low, moderate, and high SIQR severity groups showed concomitant increases in tenderness in response to digital evoked palpation (F=23.5; p<0.0000; ηp2=0.23; MR=.54), blood pressure cuff evoked pain (F=17.0; p<0.0000; ηp2=0.18; MR=0.48) and number of pain location (F=38.8; p<0.0000; ηp2=0.33; MR.59). Strongest differences in SIQR severity were found in response to the question, "I have a persistent deep aching over most of my body" (F=87.5; p<0.0000; ηp2=0.53; MR=0.74). Conclusions: The SIQR strongly predicts the central features of FM tenderness and pain including its widespreadness and its multifaceted character. We propose that tenderness, both locally and over most of the body, attendant to the SIQR is the hallmark of the FM phenotype: tenderness is focal, diffuse, deep, and superficial.
Databáze:	MEDLINE
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