ERICA: cardiovascular risks associated with oral contraceptive use among Brazilian adolescents.

Autor:	Barros BS; Universidade do Estado do Rio de Janeiro, Faculdade de Ciência Médicas, Núcleo de Estudos da Saúde do Adolescente, Programa de Pós-Graduação em Ciências Médicas, Rio de Janeiro, RJ, Brazil. Electronic address: bsbarros.med@gmail.com., Kuschnir MCC; Universidade do Estado do Rio de Janeiro, Faculdade de Ciência Médicas, Núcleo de Estudos da Saúde do Adolescente, Programa de Pós-Graduação em Ciências Médicas, Rio de Janeiro, RJ, Brazil., Kuschnir FC; Universidade do Estado do Rio de Janeiro, Faculdade de Ciências Médicas, Programa de Pós-Graduação em Ciências Médicas, Departamento de Pediatria, Rio de Janeiro, RJ, Brazil., Jordão ÉAOC; Universidade do Estado do Rio de Janeiro, Faculdade de Ciência Médicas, Programa de Pós-Graduação em Ciências Médicas, Rio de Janeiro, RJ, Brazil.
Jazyk:	angličtina
Zdroj:	Jornal de pediatria [J Pediatr (Rio J)] 2022 Jan-Feb; Vol. 98 (1), pp. 53-59. Date of Electronic Publication: 2021 May 15.
DOI:	10.1016/j.jped.2021.03.006
Abstrakt:	Objective: To investigate the association between oral contraceptive use and cardiovascular risks, including metabolic syndrome and their components in Brazilian adolescents. Method: This study used data from the Study of Cardiovascular Risks in Adolescents (Estudo de Riscos Cardiovasculares em Adolescentes - ERICA), a nationwide, cross-sectional, school-based study with individuals aged 12-17 years. Sociodemographic variables and OC use were assessed by a self-administered questionnaire. International Diabetes Federation criteria were used to define metabolic syndrome. Descriptive statistics were reported as prevalence and their respective confidence interval of 95% of oral contraceptives according to variables. Logistic regression was performed. Crude and adjusted odds ratios were calculated. Results: This subsample was composed of 22,682 female adolescents, of which 12.65% reported using oral contraceptives and their use was associated with hypertension and hypertriglyceridemia. These associations remained statistically significant after adjusting for age, school region, race, and tobacco use with an increase of 2.68 (1.66 - 4.32) and 3.45 (2.56 - 4.65) times, respectively. Conclusion: The present study was the first to examine the association between the use of oral contraceptives and cardiovascular risk factors among the largest number of female Brazilian adolescents. This method was significantly associated with hypertension, hypertriglyceridemia. Teenagers using oral contraceptives should be monitored for side effects, including blood pressure measurements and advised to avoid smoking. Competing Interests: Conflicts of interest The authors declare no conflicts of interest. (Copyright © 2021 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu