Evaluation of subclinical chronic sun damage in the skin via the detection of long-lasting ultraweak photon emission.

Autor: Gabe Y; Biological Science Research, Kao Corporation, Odawara, Japan., Takeda K; Skin Care Research, Kao Corporation, Sumida, Japan., Tobiishi M; Biological Science Research, Kao Corporation, Odawara, Japan., Kikuchi S; Skin Care Research, Kao Corporation, Sumida, Japan., Tsuda K; Analytical Science Research, Kao Corporation, Japan, Haga., Haryuu Y; Skin Care Research, Kao Corporation, Sumida, Japan., Nakajima Y; Skin Care Research, Kao Corporation, Sumida, Japan., Inomata Y; Skin Care Research, Kao Corporation, Sumida, Japan., Nakamura S; Analytical Science Research, Kao Corporation, Japan, Haga., Murase D; Biological Science Research, Kao Corporation, Odawara, Japan., Tokunaga S; Analytical Science Research, Kao Corporation, Japan, Haga., Miyaki M; Skin Care Research, Kao Corporation, Sumida, Japan., Takahashi Y; Biological Science Research, Kao Corporation, Odawara, Japan.
Jazyk: angličtina
Zdroj: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) [Skin Res Technol] 2021 Nov; Vol. 27 (6), pp. 1064-1071. Date of Electronic Publication: 2021 May 17.
DOI: 10.1111/srt.13059
Abstrakt: Background: It is well known that solar radiation accelerates skin photoaging. To evaluate subclinical photodamage in the skin especially from the early phase of ultraviolet (UV)-induced damage, we have focused on ultraweak photon emission (UPE), also called biophotons. Our previous study reported that the amount of long-lasting UPE induced by UV, predominantly from lipid peroxidation, is a valuable indicator to assess cutaneous photodamage even at a suberythemal dose, although it was only applied to evaluate acute UV damage. The aim of this study was to further investigate whether long-lasting UPE could also be a useful marker to assess subclinical chronic sun damage in the course of skin photoaging.
Materials and Methods: Forty-three Japanese females in their 20s were recruited and were divided into two groups according to their history of sun exposure based on a questionnaire (high- and low-sun-exposure groups). Several skin properties on the cheek and outer forearm were measured in addition to UV-induced UPE.
Results: Among the skin properties measured, water content, average skin roughness, and the lateral packing of lipids in the stratum corneum were significantly deteriorated in the high-sun-exposure group as were changes in some skin photoaging scores such as pigmented spots and wrinkles. In addition, those skin properties were correlated with the UPE signals, suggesting the possible impact of oxidative stress on chronic skin damage.
Conclusion: Subtle oxidative stress detected by long-lasting UPE may contribute to subclinical cutaneous damage at the beginning phase of chronic sun exposure, which potentially enhances skin photoaging over a lifetime.
(© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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