Does the maternal-fetal transmission of SARS-CoV-2 occur during pregnancy?

Autor: Hijona Elósegui JJ; Servicio de Obstetricia y Ginecología, Hospital Universitario Materno-Infantil de Jaén, Jaén, Spain. Electronic address: jesushijona@gmail.com., Carballo García AL; Servicio de Obstetricia y Ginecología, Hospital Universitario Materno-Infantil de Jaén, Jaén, Spain., Fernández Risquez AC; Servicio de Obstetricia y Ginecología, Hospital Universitario Materno-Infantil de Jaén, Jaén, Spain., Bermúdez Quintana M; Servicio de Obstetricia y Ginecología, Hospital Universitario Materno-Infantil de Jaén, Jaén, Spain., Expósito Montes JF; Servicio de Pediatría, Hospital Universitario Materno-Infantil de Jaén, Jaén, Spain.
Jazyk: angličtina
Zdroj: Revista clinica espanola [Rev Clin Esp (Barc)] 2021 Feb; Vol. 221 (2), pp. 93-96. Date of Electronic Publication: 2020 Jul 10.
DOI: 10.1016/j.rceng.2020.06.002
Abstrakt: Background and Objetive: On January 7th, 2020, a new coronavirus, SARS-CoV-2, was identified, as responsible for a new human disease: COVID-19. Given its recent appearance, our current knowledge about the possible influence that this disease can exert on pregnancy is very limited. One of the unknowns to be solved is whether there is a vertical transmission of the infection during pregnancy.
Patients and Methods: Using the Real-time Polymerase Chain Reaction techniques for SARS-CoV-2 nucleic acids, the possible presence of this germ in vaginal discharge and amniotic fluid was investigated in four pregnant Caucasian patients affected by mild acute symptoms of COVID-19 during the second trimester of pregnancy.
Results: There is no laboratory evidence to suggest a possible passage of SARS-CoV-2 from the infected mother to the amniotic fluid.
Conclusions: It is necessary to expand the investigation of COVID-19 cases diagnosed during pregnancy to clarify the real influence that SARS-CoV-2 has on pregnant women and their offspring, as well as those factors that modulate the disease.
(Copyright © 2020 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.)
Databáze: MEDLINE