Case Report: Use of PET/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like Lymphoma.

Autor:	Chen CL; Veterinary Medical Center, The Ohio State University, Columbus, OH, United States., Cook MR; Veterinary Medical Center, The Ohio State University, Columbus, OH, United States., Brown ME; Veterinary Medical Center, The Ohio State University, Columbus, OH, United States., Lumbrezer-Johnson S; Veterinary Medical Center, The Ohio State University, Columbus, OH, United States., Hostnik ET; Veterinary Medical Center, The Ohio State University, Columbus, OH, United States., Lapsley JM; Veterinary Medical Center, The Ohio State University, Columbus, OH, United States., Lerche P; Veterinary Medical Center, The Ohio State University, Columbus, OH, United States., Wavreille VA; Department of Surgery, University of Zurich, Zurich, Switzerland., Menendez MI; Department of Radiology, The Wright Center of Innovation in Biomedical Imaging, The Ohio State University Wexner Medical Center, Columbus, OH, United States., Knopp MV; Department of Radiology, The Wright Center of Innovation in Biomedical Imaging, The Ohio State University Wexner Medical Center, Columbus, OH, United States., Linn SC; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, United States., Premanandan C; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, United States., Selmic LE; Veterinary Medical Center, The Ohio State University, Columbus, OH, United States.
Jazyk:	angličtina
Zdroj:	Frontiers in veterinary science [Front Vet Sci] 2021 Apr 29; Vol. 8, pp. 619264. Date of Electronic Publication: 2021 Apr 29 (Print Publication: 2021).
DOI:	10.3389/fvets.2021.619264
Abstrakt:	An 8-year-old male neutered Domestic Long Hair cat was presented for a cervical swelling that was suspected to be an enlarged left retropharyngeal lymph node. In the absence of other lymphadenopathy, this was initially suspected to be Hodgkin's-like lymphoma. A positron emission tomography-computed tomography (PET/CT) scan was performed using 2-deoxy-2-[ 18 F]-fluorodeoxyglucose ( 18 F-FDG) to assess for evidence of disease in other locations to guide treatment. Multifocal increased radiopharmaceutical uptake was identified, indicating disease in multiple organs. High-grade lymphoma was confirmed on tissue biopsy. As such, systemic cytotoxic chemotherapy was recommended instead of lymph node extirpation surgery. The cat received a modified CHOP chemotherapy protocol and attained a temporary partial remission. After 2 months of treatment, the cat stopped responding to chemotherapy and was eventually euthanized due to a relapse of disease and decreased quality of life. This case describes the utility of PET/CT to guide treatment in a cat with a presentation consistent with Hodgkin's-like lymphoma. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2021 Chen, Cook, Brown, Lumbrezer-Johnson, Hostnik, Lapsley, Lerche, Wavreille, Menendez, Knopp, Linn, Premanandan and Selmic.)
Databáze:	MEDLINE
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