Frailty and Its Associated Risk Factors: First Phase Analysis of Multicentre Indonesia Longitudinal Aging Study.

Autor: Setiati S; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia.; Clinical Epidemiology and Evidence-Based Medicine Unit, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia., Soejono CH; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia., Harimurti K; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia.; Clinical Epidemiology and Evidence-Based Medicine Unit, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia., Dwimartutie N; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia., Aryana IGPS; Department of Internal Medicine, Faculty of Medicine, Universitas Udayana, Bali, Indonesia., Sunarti S; Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia., Budiningsih F; Department of Internal Medicine, Faculty of Medicine, Universitas Sebelas Maret, Solo, Indonesia., Mulyana R; Department of Internal Medicine, Faculty of Medicine, Universitas Andalas, Padang, Indonesia., Dwipa L; Department of Internal Medicine, Faculty of Medicine, Universitas Padjajaran, Bandung, Indonesia., Sudarso A; Department of Internal Medicine, Faculty of Medicine, Universitas Hasanuddin, Makasar, Indonesia., Rensa R; Department of Internal Medicine, Faculty of Medicine, Universitas Atma Jaya, Jakarta, Indonesia., Istanti R; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia., Azwar MK; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia., Marsigit J; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia.
Jazyk: angličtina
Zdroj: Frontiers in medicine [Front Med (Lausanne)] 2021 Apr 29; Vol. 8, pp. 658580. Date of Electronic Publication: 2021 Apr 29 (Print Publication: 2021).
DOI: 10.3389/fmed.2021.658580
Abstrakt: Background: National long-term care development requires updated epidemiological data related to frailty. We aimed to find the prevalence of frailty and its associated factors among Indonesian elderly. Methods: We conducted first-phase cross-sectional analysis of Indonesia Longitudinal Aging Study (INALAS) data collected from community-dwelling outpatients aged 60 years and older without acute illness in nine geriatric service care centres. Descriptive, bivariate and multivariate analyses were conducted. Results: Among 908 elderly in this study, 15.10% were robust, 66.20% were pre-frail, and 18.70% were frail. Functional dependence was associated with frailty among Indonesian elderly (OR 5.97, 95% CI 4.04-8.80). Being depressed and at risk for malnutrition were also associated with frailty with OR 2.54, 95% CI 1.56-4.12, and OR 2.56, 95% CI 1.68-3.90, respectively. Prior history of fall (OR 1.77, 95% CI 1.16-2.72) and hospitalization (OR 1.46, 95% CI 0.97-2.20) in the previous 12 months were associated with frailty. There is also significant association between poly pharmacy and frailty (OR 2.42, 95% CI 1.50-3.91). Conclusion: Approximately one in five Indonesian community-dwelling elderly was frail. Frailty is associated with functional dependence, being at risk for malnutrition or being malnourished, depression, history of fall, history of hospitalization, and poly pharmacy. There may be bidirectional relationships between the risk factors and frailty. The development of long-term care in Indonesia should be considered, without forcing the elderly who need it.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2021 Setiati, Soejono, Harimurti, Dwimartutie, Aryana, Sunarti, Budiningsih, Mulyana, Dwipa, Sudarso, Rensa, Istanti, Azwar and Marsigit.)
Databáze: MEDLINE