Post-Traumatic Seizures: A Deep-Dive Into Pathogenesis.

Autor: Anwer F; Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Oliveri F; Cardiology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Kakargias F; Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Panday P; Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Arcia Franchini AP; Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Iskander B; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Hamid P; Neurology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2021 Apr 10; Vol. 13 (4), pp. e14395. Date of Electronic Publication: 2021 Apr 10.
DOI: 10.7759/cureus.14395
Abstrakt: Post-traumatic seizures (PTS) have become an emerging challenge for neurologists worldwide with the rise of brain injuries. Trauma can lead to various outcomes, ranging from naive spasms to debilitating post-traumatic epilepsy (PTE). In this article, we will explore the pathogenesis of convulsions following a concussion. We will look at multiple studies to explain the various structural, metabolic, and inflammatory changes leading to seizures. Additionally, we will explore the association between severity and location of injury and PTE. PTE's pathophysiology is not entirely implicit, and we are still in the dark as to which anti-epileptic drugs will be useful in circumventing these attacks. The purpose of this narrative review is to explain the post-traumatic brain changes in detail so that such attacks can be either thwarted or treated more resourcefully in the future.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2021, Anwer et al.)
Databáze: MEDLINE