Neither B cell nor T cell - The unique group of innate lymphoid cells.

Autor: Kanellopoulos JM; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Paris-Saclay University, Gif-sur-Yvette, France., Ojcius DM; Department of Biomedical Sciences, University of the Pacific, Arthur Dugoni School of Dentistry, San Francisco, CA, USA. Electronic address: dojcius@pacific.edu.
Jazyk: angličtina
Zdroj: Biomedical journal [Biomed J] 2021 Apr; Vol. 44 (2), pp. 112-114. Date of Electronic Publication: 2021 Apr 16.
DOI: 10.1016/j.bj.2021.04.001
Abstrakt: This special issue contains four review articles that analyze the development and biology of innate lymphoid cells (ILCs), which are the most recently-discovered group of innate immune cells. This unique group of lymphoid cells lacks the RAG gene and consequently does not express B cell nor T cell antigen-specific receptors. They are abundant at mucosal surfaces, where they play a role in immunity and homeostasis. The ILCs are the focus of intensive research efforts to understand their development and function.
(Copyright © 2021 Chang Gung University. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE