Hair of the mouse: A skin bacteria "cocktail" gets follicles back on their feet.

Autor: Gonzalez JR; Biomedical Sciences Program, University of California, San Francisco, CA 94143, USA; Department of Dermatology, University of California, San Francisco, CA 94143, USA., Merana GR; Biomedical Sciences Program, University of California, San Francisco, CA 94143, USA; Department of Dermatology, University of California, San Francisco, CA 94143, USA., Scharschmidt TC; Department of Dermatology, University of California, San Francisco, CA 94143, USA. Electronic address: tiffany.scharschmidt@ucsf.edu.
Jazyk: angličtina
Zdroj: Cell host & microbe [Cell Host Microbe] 2021 May 12; Vol. 29 (5), pp. 742-744.
DOI: 10.1016/j.chom.2021.04.011
Abstrakt: Microbes can boost cutaneous immune defense and skin reparative capacity. However, mechanistic understanding, especially of the latter, remains sparse. In this issue of Cell Host & Microbe, Wang et al. (2021) shed light on this, demonstrating that bacteria contribute to hair follicle neogenesis after skin wounding via keratinocyte-intrinsic IL-1R1 signaling.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE