Delayed, transient and self-resolving neutropenia following COVID-19 pneumonia.

Autor: Mank VMF; Internal Medicine, Tripler Army Medical Center, Honolulu, Hawaii, USA victoriammank@gmail.com., Mank J; University of New England, Biddeford, Maine, USA., Ogle J; Internal Medicine, Tripler Army Medical Center, Honolulu, Hawaii, USA., Roberts J; Rheumatology, Tripler Army Medical Center, Honolulu, Hawaii, USA.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2021 May 12; Vol. 14 (5). Date of Electronic Publication: 2021 May 12.
DOI: 10.1136/bcr-2021-242596
Abstrakt: A novel coronaravirus, identified as SARS-CoV-2, spread throughout the world in 2020. The COVID-19 pandemic has led to many discoveries and clinical manifestations. A young patient is presented with new, self-resolving neutropenia presenting weeks after a prolonged hospital stay for COVID-19 pneumonia. Workup included analysis for underlying infection, nutritional abnormalities, malignancy, medication and toxin exposure, all of which were negative. From 2020 to the present, few reports have described neutropenia associated with a recent COVID-19 infection. In particular, no reports have described a delayed presentation of neutropenia. The authors would like to propose that the significant inflammatory response associated with COVID-19 is likely what led to this patient's postviral neutropenia. Furthermore, in young healthy patients, bone marrow biopsy may be deferred and a watchful-waiting approach may be taken to assess for neutropenia resolution.
Competing Interests: Competing interests: None declared.
(© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE