Transplant of Elderly Patients: Is There an Upper Age Cutoff?
| Autor: | Cottone C; Department of Internal Medicine at Northwestern Medicine McHenry Hospital, Rosalind Franklin University of Medicine and Science, 4309 West Medical Center Drive, McHenry, IL 60050, USA. Electronic address: Claudia.cottone13@gmail.com., Pena Polanco NA; Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Suite 1105, Miami, FL 33136, USA., Bhamidimarri KR; Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Suite 1144, Miami, FL 33136, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Clinics in liver disease [Clin Liver Dis] 2021 Feb; Vol. 25 (1), pp. 209-227. Date of Electronic Publication: 2020 Oct 21. |
| DOI: | 10.1016/j.cld.2020.09.001 |
| Abstrakt: | Increased life expectancy and advances in the care of chronic liver disease has increased the number of elderly patients needing liver transplant. Organ donation policies prioritize transplant to the sickest. There is an ongoing debate with regard to balancing the principles of equity and utility. Several hospitals have adopted center-specific policies and there has been an increased trend of transplant in elderly patients since 2002. Appropriate patient selection and long-term outcomes in the setting of limited organ availability pose several challenges. This article reviews the data and discusses the pros and cons of transplants in the elderly. Competing Interests: Disclosure C. Cottone and N.P. Polanco have nothing to disclose. K.R. Bhamidimarri receives research grants from Allergan, Gilead, Genfit, Mallinckrodt, Viking therapies, and Hepquant; participates in scientific advisory boards for Gilead, Abbvie, Mallinckrodt, and Intercept, and receives speaker honoraria from Alexion and Intercept. (Copyright © 2020 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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