Biological markers and follow-up after discharge home of patients with COVID-19 pneumonia.

Autor:	Gutiérrez Gabriel S; Servicio de Urgencias, Hospital Universitario de Fuenlabrada, Madrid, España., Domínguez García MJ; Servicio de Urgencias, Hospital Universitario de Fuenlabrada, Madrid, España., Pérez Mañas G; Medicina Familiar y Comunitaria, Hospital Universitario de Fuenlabrada, Madrid, España., Moreno García N; Medicina Familiar y Comunitaria, Hospital Universitario de Fuenlabrada, Madrid, España., Silvan Domínguez M; Medicina Familiar y Comunitaria, Hospital Universitario de Fuenlabrada, Madrid, España., Andrés EM; Grupo 'gestión del paciente sangrante' idiPaz-Hospital Universitario La Paz, Madrid, España. Universidad Rey Juan Carlos, Madrid, España.
Jazyk:	English; Spanish; Castilian
Zdroj:	Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias [Emergencias] 2021 Jun; Vol. 33 (3), pp. 174-180.
Abstrakt:	Objectives: We aimed to analyze the clinical course of patients discharged from our emergency departament (ED) with pneumonia symptoms compatible with a diagnosis of COVID-19. Material and Methods: We followed 102 patients discharged home with a diagnosis of pneumonia compatible with COVID19 between March 12 and 21, 2020, in our hospital in the southern part of the autonomous community of Madrid. Descriptive statistics (medians and interquartile ranges or frequencies, as appropriate) were compiled for the main variables. Treatments and prognoses were compared with 􀁆2, Kruskal-Wallis, or Mann-Whitney tests. The data then underwent logistic regression analysis. Results: Most patients (accounting for 74.5% of the discharges) were treated with hydroxychloroquine alone. The readmission rate was 15.7%; the ED revisiting rate was 25.7%. Admission was associated with an elevated lactate dehydrogenase (LDH) level (P=.011), elevated creatine kinase (CK) (P=.004), and lymphopenia (P=.034). Hypertension and chronic obstructive pulmonary disease were also related to admission. Ischemic heart disease was associated with longer duration of symptoms. Conclusion: Lymphopenia, and elevated LDH and CK levels predicted the need for hospital admission better than other traditional biological markers in patients with mild to moderate symptoms. Telephone follow-up proved useful for dealing with the overloading of health care services.
Databáze:	MEDLINE
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