| Autor: |
Watts DP; Department of Physics, University of York, Heslington, York, UK. daniel.watts@york.ac.uk., Bordes J; Department of Physics, University of York, Heslington, York, UK., Brown JR; Department of Physics, University of York, Heslington, York, UK., Cherlin A; Kromek Group, Sedgefield, County Durham, UK., Newton R; Department of Physics, University of York, Heslington, York, UK., Allison J; Geant4 Associates International Ltd., Hebden Bridge, UK.; Department of Physics and Astronomy, University of Manchester, Manchester, UK., Bashkanov M; Department of Physics, University of York, Heslington, York, UK., Efthimiou N; Department of Physics, University of York, Heslington, York, UK.; PET Research Centre, School of Health Sciences, University of Hull, Hull, UK., Zachariou NA; Department of Physics, University of York, Heslington, York, UK. |
| Abstrakt: |
Positron Emission Tomography (PET) is a widely-used imaging modality for medical research and clinical diagnosis. Imaging of the radiotracer is obtained from the detected hit positions of the two positron annihilation photons in a detector array. The image is degraded by backgrounds from random coincidences and in-patient scatter events which require correction. In addition to the geometric information, the two annihilation photons are predicted to be produced in a quantum-entangled state, resulting in enhanced correlations between their subsequent interaction processes. To explore this, the predicted entanglement in linear polarisation for the two photons was incorporated into a simulation and tested by comparison with experimental data from a cadmium zinc telluride (CZT) PET demonstrator apparatus. Adapted apparati also enabled correlation measurements where one of the photons had undergone a prior scatter process. We show that the entangled simulation describes the measured correlations and, through simulation of a larger preclinical PET scanner, illustrate a simple method to quantify and remove the unwanted backgrounds in PET using the quantum entanglement information alone. |
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