Vaginal Isolates of Candida glabrata Are Uniquely Susceptible to Ionophoric Killer Toxins Produced by Saccharomyces cerevisiae.

Autor:	Fredericks LR; Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA., Lee MD; Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA., Eckert HR; Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA., Li S; Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA., Shipley MA; Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA., Roslund CR; Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA., Boikov DA; Department of Internal Medicine, Division Infectious Diseases, Wayne State University School of Medicine, Detroit, Michigan, USA., Kizer EA; Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA., Sobel JD; Department of Internal Medicine, Division Infectious Diseases, Wayne State University School of Medicine, Detroit, Michigan, USA., Rowley PA; Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA.
Jazyk:	angličtina
Zdroj:	Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Jun 17; Vol. 65 (7), pp. e0245020. Date of Electronic Publication: 2021 Jun 17.
DOI:	10.1128/AAC.02450-20
Abstrakt:	Compared to other species of Candida yeasts, the growth of Candida glabrata is inhibited by many different strains of Saccharomyces killer yeasts. The ionophoric K1 and K2 killer toxins are broadly inhibitory to all clinical isolates of C. glabrata from patients with recurrent vulvovaginal candidiasis, despite high levels of resistance to clinically relevant antifungal therapeutics.
Databáze:	MEDLINE
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