Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate.

Autor:	Figueiredo MA; Universidade de São Paulo (USP), Faculdade de Odontologia, Departamento de Estomatologia, Centro de Atendimento a Pacientes Especiais, São Paulo, SP, Brasil., Medeiros FB; Universidade de São Paulo (USP), Faculdade de Odontologia, Departamento de Estomatologia, Centro de Atendimento a Pacientes Especiais, São Paulo, SP, Brasil., Ortega KL; Universidade de São Paulo (USP), Faculdade de Odontologia, Departamento de Estomatologia, Centro de Atendimento a Pacientes Especiais, São Paulo, SP, Brasil.
Jazyk:	angličtina
Zdroj:	Autopsy & case reports [Autops Case Rep] 2020 Dec 08; Vol. 11, pp. e2020186. Date of Electronic Publication: 2020 Dec 08.
DOI:	10.4322/acr.2020.186
Abstrakt:	Although uncommon in patients under oral therapy, bisphosphonate-related osteonecrosis of the jaw (BRONJ) can be a very severe issue. Early intervention with surgical resection should be the preferable method of treating any stage of the disease, resulting in better outcomes and decreasing the morbidity of this condition. A 77-year-old female patient attended the Special Care Dentistry Centre of the University of São Paulo Faculty of Dentistry (CAPE FOUSP) complaining mainly of "an exposed bone that appeared after tooth extraction performed six months earlier". The patient was diagnosed with osteonecrosis associated with bisphosphonate (sodium ibandronate) and surgically treated with removal of bone sequestration and antibiotic therapy. The patient was followed up for six years (a total of 6 appointments), presenting good general health and no sign of bone exposure. Imaging findings showed no changes related to BRONJ either. Competing Interests: Conflict of interest: The authors declare no conflict of interest. (Copyright: © 2020 The Authors.)
Databáze:	MEDLINE
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