Large intraperitoneal lipoleiomyoma in a pre-menopausal woman: a case report.

Autor: Schaefer SL; Department of Surgery, University of Michigan School of Medicine, 1500 E. Medical Center Drive, Ann Arbor, Michigan, 48109-5932, USA., Strong AL; Department of Surgery, University of Michigan School of Medicine, 1500 E. Medical Center Drive, Ann Arbor, Michigan, 48109-5932, USA., Bahroloomi S; Department of Surgery, University of Michigan School of Medicine, 1500 E. Medical Center Drive, Ann Arbor, Michigan, 48109-5932, USA., Han J; Department of Microbiology and Immunology, The Geisel School of Medicine at Dartmouth, 1 Rope Ferry Road, Hanover, New Hampshire, 03755, USA., Whisman MK; Department of Pathology, University of Michigan School of Medicine, 1500 E. Medical Center Drive, Ann Arbor, Michigan, 48109-5932, USA., Wilkowski JM; Department of Surgery, University of Michigan School of Medicine, 1500 E. Medical Center Drive, Ann Arbor, Michigan, 48109-5932, USA., Angeles CV; Department of Surgery, University of Michigan School of Medicine, 1500 E. Medical Center Drive, Ann Arbor, Michigan, 48109-5932, USA. angelesc@med.umich.edu.
Jazyk: angličtina
Zdroj: World journal of surgical oncology [World J Surg Oncol] 2021 May 08; Vol. 19 (1), pp. 144. Date of Electronic Publication: 2021 May 08.
DOI: 10.1186/s12957-021-02256-9
Abstrakt: Background: Lipoleiomyoma is a rare, benign variant of the commonplace uterine leiomyoma. Unlike leiomyoma, these tumors are composed of smooth muscle cells admixed with mature adipose tissue. While rare, they are most frequently identified in the uterus, but even more infrequently have been described in extrauterine locations.
Case Presentation: We describe a case report of a 45-year-old woman with a history of in vitro fertilization pregnancy presenting 6 years later with abdominal distention and weight loss found to have a 30-cm intra-abdominal lipoleiomyoma. While cross-sectional imaging can narrow the differential diagnosis, histopathological analysis with stains positive for smooth muscle actin, desmin, and estrogen receptor, but negative for HMB-45 confirms the diagnosis of lipoleiomyoma. The large encapsulated tumor was resected en bloc. The patients post-operative course was uneventful and her symptoms resolved.
Conclusions: Lipoleiomyoma should be considered on the differential diagnosis in a woman with a large intra-abdominal mass. While considered benign, resection should be considered if the mass is symptomatic, and the diagnosis is unclear or there is a concern for malignancy.
Databáze: MEDLINE
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