[Influence of the degree of anaemia on the prognosis of older adults with heart failure (SPAN-HF study)].

Autor:	Grau Amorós J; Hospital Municipal de Badalona, Badalona, España. Electronic address: 11426jga@comb.cat., García García JÁ; Hospital Ntra. Sra. de Valme, Sevilla, España., Mira Escartí JA; Hospital Ntra. Sra. de Valme, Sevilla, España., Serrado Iglesias A; Hospital Municipal de Badalona, Badalona, España., Moreno García MC; Servicio de Medicina Interna, Hospital de Manises, Manises, Valencia, España., Manzano L; Servicio de Medicina Interna, Hospital Universitario Ramón y Cajal, Universidad de Alcalá (IRYCIS), Madrid, España., Quesada Simón MA; Servicio de Medicina Interna, Hospital Universitario La Paz, Madrid, España., Dávila Ramos MF; Servicio de Medicina Interna, Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, España., Casado Cerrada J; Servicio de Medicina Interna, Hospital Universitario de Getafe, Madrid, España., González Franco Á; Servicio de Medicina Interna, Hospital Universitario Central de Asturias, Oviedo, Asturias, España., Montero-Pérez-Barquero M; Servicio de Medicina Interna, IMIBIC/Hospital Reina Sofía, Universidad de Córdoba, Córdoba, España.
Jazyk:	English; Spanish; Castilian
Zdroj:	Medicina clinica [Med Clin (Barc)] 2022 Feb 25; Vol. 158 (4), pp. 167-172. Date of Electronic Publication: 2021 May 04.
DOI:	10.1016/j.medcli.2021.01.016
Abstrakt:	Objective: To assess whether a sustained optimal haemoglobin value in the 3 months after admission for heart failure (HF) decompensation reduces morbidity and mortality during the 12 months after admission for acute HF. Patients and Method: Retrospective study of the 1408 patients older than 65 years included in the RICA registry divided into 3 groups: no anaemia (group A), recovered anaemia (group B), and persistent anaemia (group C), according to haemoglobin levels on admission, and 3 months after discharge. Kaplan-Meier curves were constructed, comparing the groups using the log-rank test and a Cox regression model was performed to analyse survival. Results: 578 (41.1%), 299 (21.2%) and 531 (37.7%) were included in groups A, B and C, respectively. We recorded a total of 768 deaths and readmissions. There were 23 (4%), 12 (4%) and 49 (9.2%), (p=.001) individuals who died due to HF and 154 (27%), 73 (24%) and 193 (36%) (P<.001) admissions for this pathology, respectively. Patients with persistent anaemia had a higher risk of death (RR 1.29, 95% CI 1.04-1.61, P=.024) or readmission (1.92, 95% CI 1.16-3, 19; P=.012) due to HF. Conclusions: Persistent anaemia in the months after admission for HF increases morbidity and mortality in the subsequent year. (Copyright © 2021 Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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