Treatment challenges in adult female acne and future directions.

Autor: Bagatin E; Universidade Federal De São Paulo, São Paulo, Brazil., Rocha MADD; Universidade Federal De São Paulo, São Paulo, Brazil., Freitas THP; Santa Casa Medical and Hospital School, Dermatology Clinic, São Paulo, Brazil., Costa CS; Department of Specialized Medicine, Discipline of Dermatology - Universidade Federal Do Piauí, Teresina, Brazil.
Jazyk: angličtina
Zdroj: Expert review of clinical pharmacology [Expert Rev Clin Pharmacol] 2021 Jun; Vol. 14 (6), pp. 687-701. Date of Electronic Publication: 2021 May 12.
DOI: 10.1080/17512433.2021.1917376
Abstrakt: Introduction : Acne is a chronic, inflammatory, and immune-mediated disease of the pilosebaceous unit, highly prevalent in adolescents. However, an increasing number of adults over 25 years old with facial acne, particularly women, have been observed. It is considered a different disease when compared to acne vulgaris. Face is the mainly involved area with inflammatory lesions and more sensitive skin, pointing out the need of a holistic approach. Areas covered : We performed a comprehensive literature search on PubMed database, up to January 2021, regarding adult female acne. We synthesized data about pathogenesis; differences compared to acne vulgaris; and treatment, with focus in the management challenges and perspectives. Expert opinion : It is essential to value the negative impact on quality of life of adult female acne, independently of severity. The disease has prolonged evolution, and patient might be resilient once the improvement, regardless of the treatment option, will just be noticeable after 3 months. Aggravating factors should be clearly discussed, such as the need of changing many habits, especially lesions manipulation. The therapeutic regimen includes make-up and tailored skin care (considering proneness to sensitivity), while anti-acne drugs should be chosen in accordance with desire to be pregnant, presence of pregnancy or breastfeeding.
Databáze: MEDLINE