Proposed quality performance indicators of sentinel lymph node biopsy for cutaneous melanoma.

Autor: Wen D; Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand., Martin RCW; Department of Cutaneous Oncology, North Shore Hospital, Waitematā District Health Board, Auckland, New Zealand.; Melanoma Unit, Auckland, New Zealand.
Jazyk: angličtina
Zdroj: ANZ journal of surgery [ANZ J Surg] 2021 Dec; Vol. 91 (12), pp. 2644-2649. Date of Electronic Publication: 2021 May 06.
DOI: 10.1111/ans.16914
Abstrakt: Background: Melanoma is a leading cause of morbidity and mortality in Australia and New Zealand. New Zealand has the highest melanoma incidence in the world alongside Australia at 54 per 100 000 persons. The aim of this study is to conduct a retrospective quality audit of sentinel lymph nodal biopsy (SLNB) practices from 2007 to 2019 of a high-volume melanoma surgeon. Primary outcome was false negative rate (FNR). Secondary outcomes were sentinel node (SN) identification and removal rate, and complication rates.
Methods: A database was maintained, containing n = 553 consecutive SLNB's for cutaneous melanoma from 31 August 2007 to 31 August 2019. Patient characteristics and details of the primary lesion, sentinel lymph node biopsy, recurrence and complications were recorded.
Results: SN's were successfully identified in 444 (99.6%) out of 446 patients with an FNR of 9.1%. Positive SN's were identified in 70 (12.7%) SLNB's. Complications occurred in 76 out of 553 (13.7%) SLNB's. A review of internationally published literature reveals an SN identification rate of 94.4-99.5% with an FNR of 4.0-37.5%. SLNB is the best staging tool for melanoma and gives potential access to adjuvant systemic treatment if >1 mm deposits are found. It is a day-stay procedure with a low-complication rate.
Conclusion: SLNB is a safe and reliable procedure utilized for cutaneous melanoma. We propose our data should be used alongside international SN series to establish Quality Performance Indicators to improve melanoma management.
(© 2021 Royal Australasian College of Surgeons.)
Databáze: MEDLINE
Externí odkaz: