Extract of neem (Azadirachta indica) leaf exhibits bactericidal effect against multidrug resistant pathogenic bacteria of poultry.

Autor: Ali E; Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh., Islam MS; Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh., Hossen MI; Livestock Division, Bangladesh Agricultural Research Council, Dhaka, Bangladesh., Khatun MM; Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh., Islam MA; Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Jazyk: angličtina
Zdroj: Veterinary medicine and science [Vet Med Sci] 2021 Sep; Vol. 7 (5), pp. 1921-1927. Date of Electronic Publication: 2021 May 06.
DOI: 10.1002/vms3.511
Abstrakt: The aim of the study was to determine the efficacy of neem leaf extract against multidrug resistant (MDR) pathogenic bacteria. Laboratory stock culture of Pasteurella multocida, Salmonella pullorum, Salmonella gallinarum and Escherichia coli was revived. Antibiogram profiles of these bacteria were determined by disc diffusion method. Ethanolic extract of neem leaf was prepared. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of neem leaf extract (112.5, 100, 50, 25, 12.5, 6.25 and 3.12 mg/ml) against MDR pathogenic bacteria of poultry were determined by double dilution method. The MIC and MBC of the neem leaf extract were 12.5 and 25 mg/ml, respectively for P. multocida, 50 and 100 mg/ml for S. pullorum and S. gallinarum, 100 and 112.5 mg/ml for E. coli. Neem leaf extracts exhibited bactericidal effect against MDR pathogenic bacteria of poultry.
(© 2021 The Authors. Veterinary Medicine and Science published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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