Outcomes of hospitalized patients with COVID-19 according to level of frailty.

Autor:	Andrés-Esteban EM; Grupo PBM, Instituto de Investigación-IdiPaz, Madrid, Madrid, Spain.; Universidad Rey Juan Carlos, Madrid, Madrid, Spain., Quintana-Diaz M; Grupo PBM, Instituto de Investigación-IdiPaz, Madrid, Madrid, Spain.; Servicio de Medicina Intensiva, Hospital Universitario La Paz, Madrid, Madrid, Spain., Ramírez-Cervantes KL; Grupo PBM, Instituto de Investigación-IdiPaz, Madrid, Madrid, Spain.; Departamento de Prevención, Asociación Española contra el Cáncer, Madrid, Madrid, Spain., Benayas-Peña I; Grupo PBM, Instituto de Investigación-IdiPaz, Madrid, Madrid, Spain., Silva-Obregón A; Grupo PBM, Instituto de Investigación-IdiPaz, Madrid, Madrid, Spain.; Servicio de Medicina Intensiva, Hospital Universitario de Guadalajara, Guadalajara, Guadalajara, Spain., Magallón-Botaya R; Departamento de Medicina, Psiquiatría y Dermatología, Universidad de Zaragoza, Zargoza, Aragón, Spain., Santolalla-Arnedo I; Universidad de La Rioja, Centro de Investigación Biomédica de La Rioja-CIBIR, Logroño, La Rioja, Spain., Juárez-Vela R; Grupo PBM, Instituto de Investigación-IdiPaz, Madrid, Madrid, Spain.; Universidad de La Rioja, Centro de Investigación Biomédica de La Rioja-CIBIR, Logroño, La Rioja, Spain., Gea-Caballero V; Nursing School La Fe., Adscript center of Universidad de Valencia., Valencia, Valencia, Spain.; Research Group GREIACC, Health Research Institute La Fe., Valencia, Valencia, Spain.
Jazyk:	angličtina
Zdroj:	PeerJ [PeerJ] 2021 Apr 13; Vol. 9, pp. e11260. Date of Electronic Publication: 2021 Apr 13 (Print Publication: 2021).
DOI:	10.7717/peerj.11260
Abstrakt:	Background: The complications from coronavirus disease 2019 (COVID-19) have been the subject of study in diverse scientific reports. However, many aspects that influence the prognosis of the disease are still unknown, such as frailty, which inherently reduces resistance to disease and makes people more vulnerable. This study aimed to explore the complications of COVID-19 in patients admitted to a third-level hospital and to evaluate the relationship between these complications and frailty. Methods: An observational, descriptive, prospective study was performed in 2020. A sample of 254 patients from a database of 3,112 patients admitted to a high-level hospital in Madrid, Spain was analyzed. To assess frailty (independent variable) the Clinical Frailty Scale (CFS) was used. The outcome variables were sociodemographic and clinical, which included complications, length of stay, intensive care unit (ICU) admission and prognosis. Results: A total of 13.39% of the patients were pre-frail and 17.32% were frail. Frail individuals had a shorter hospital stay, less ICU admission, higher mortality and delirium, with statistical significance. Conclusion: Frailty assessment is a crucial approach in patients with COVID-19, given a higher mortality rate has been demonstrated amongst frail patients. The CFS could be a predictor of mortality in COVID-19. Competing Interests: The authors declare that they have no competing interests. (© 2021 Andrés-Esteban et al.)
Databáze:	MEDLINE
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