Ultrasound-Guided Pudendal Nerve Block in Patients Undergoing Open Hemorrhoidectomy: A Post-Hoc Cost-Effectiveness Analysis from a Double-Blind Randomized Controlled Trial.

Autor:	Mongelli F; Department of Surgery, Ospedale Regionale di Lugano, Lugano, Switzerland., Lucchelli M; Financial Department, Ospedale Regionale di Bellinzona e Valli, Bellinzona, Switzerland., La Regina D; Department of Surgery, Ospedale Regionale di Bellinzona e Valli, Bellinzona, Switzerland., Christoforidis D; Department of Surgery, Ospedale Regionale di Lugano, Lugano, Switzerland., Saporito A; Department of Anesthesia, Ospedale Regionale di Bellinzona e Valli, Bellinzona, Switzerland., Vannelli A; Department of Surgery, Ospedale Valduce, Como, Italy., Di Giuseppe M; Department of Surgery, Ospedale Regionale di Bellinzona e Valli, Bellinzona, Switzerland.
Jazyk:	angličtina
Zdroj:	ClinicoEconomics and outcomes research : CEOR [Clinicoecon Outcomes Res] 2021 Apr 28; Vol. 13, pp. 299-306. Date of Electronic Publication: 2021 Apr 28 (Print Publication: 2021).
DOI:	10.2147/CEOR.S306138
Abstrakt:	Background: Pudendal nerve block (PNB) has been demonstrated to reduce postoperative pain and re-admission rates after open hemorrhoidectomy and may reduce costs but, to date, no study has reported data on this aspect. The aim of our study was to perform a cost analysis on PNB use in in- and outpatients undergoing open hemorrhoidectomy. Methods: From January 2018 to December 2019, patients undergoing open hemorrhoidectomy were included and randomized to undergo spinal anesthesia either with or without the PNB. Clinical data, direct and indirect costs for in- and outpatients, operating time and operating theatre occupancy were recorded. A cost-effectiveness analysis based on the diagnosis-related groups (DRG) and TARMED reimbursement systems was performed. Results: Patients who underwent PNB in addition to spinal anesthesia had significantly less pain and a shorter length of hospital stay after open hemorrhoidectomy. The cost analysis included all 49 patients, 23 of whom, in addition to spinal anesthesia, received a PNB. There were no significant differences in operating theatre occupancy (p=0.662), mean operative time (p=0.610) or time required for anesthesia (p=0.124). Direct costs were comparable (482±386 vs 613±543 EUR, p=0.108), while indirect costs were significantly lower in the PNB group (2606±816 vs 2769±1506 EUR, p=0.005). We estimated an incremental cost-effectiveness ratio (ICER) of -243 ± 881 EUR/pain unit on the VAS. Conclusion: Despite limitations, the ultrasound-guided PNB seems to reduce costs in patient undergoing open hemorrhoidectomy under spinal anesthesia. It was shown to be clinically beneficial and cost-effective, and therefore recommendable in patients undergoing open hemorrhoidectomy. Competing Interests: All authors have no conflicts of interest or financial ties to disclose. (© 2021 Mongelli et al.)
Databáze:	MEDLINE
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