Waterhouse-Friderichsen syndrome in a cat with Klebsiella spp. infection.

Autor: Cole LP; Department of Clinical Science and Services, The Royal Veterinary College, Hatfield, UK., Hardas A; Department of Pathobiology and Population Sciences, The Royal Veterinary College, Hatfield, UK., Priestnall SL; Department of Pathobiology and Population Sciences, The Royal Veterinary College, Hatfield, UK., Tinson EW; Department of Clinical Science and Services, The Royal Veterinary College, Hatfield, UK.
Jazyk: angličtina
Zdroj: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) [J Vet Emerg Crit Care (San Antonio)] 2021 Jul; Vol. 31 (4), pp. 531-536. Date of Electronic Publication: 2021 May 05.
DOI: 10.1111/vec.13063
Abstrakt: Objective: To describe a case of Waterhouse-Friderichsen syndrome of adrenocortical failure in a cat with Klebsiella spp. infection.
Case Summary: A 12-year-old male neutered domestic short-haired cat was referred for respiratory failure requiring mechanical ventilation. The cat remained comatose despite successful weaning from the ventilator and developed a Klebsiella pneumoniae pneumonia. On day 4 of hospitalization, the cat acutely deteriorated with profound hypotension, azotemia, and hyperkalemia, which rapidly progressed to cardiac arrest. Necropsy findings revealed massive adrenal hemorrhage and intralesional bacteria, termed Waterhouse-Friderichsen syndrome. Waterhouse-Friderichsen syndrome was suspected to have been the cause of acquired adrenocortical insufficiency and sudden death of the cat.
New or Unique Information: To the authors' knowledge, this is the first report of sepsis causing Waterhouse-Friderichsen syndrome in a veterinary species.
(© 2021 The Authors. Journal of Veterinary Emergency and Critical Care published by Wiley Periodicals LLC on behalf of Veterinary Emergency and Critical Care Society.)
Databáze: MEDLINE