Prevalence of COVID-19 in children, adolescents and adults in remote education situations in the city of Fortaleza, Brazil.

Autor:	Cavalcante Pinto Júnior V; Northeast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil. Electronic address: incorcrianca@yahoo.com.br., Moura LFWG; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil., Cavalcante RC; Department of Medical Education, Nicklaus Children's Hospital, Miami, FL, USA., Lima JRC; Dr. Rocha Furtado Death Verification Service, Fortaleza, CE, Brazil., Bezerra AS; Northeast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil., de Sousa Dantas DR; Northeast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil., Amaral CML; Northeast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil., Lima DF; Northeast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil., Júnior ABV; Clinical Research Unit CH-Federal University of Ceará/EBSERH, CE, Brazil., Florindo Guedes MI; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Campus do Itaperi, Fortaleza, CE, Brazil.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2021 Jul; Vol. 108, pp. 20-26. Date of Electronic Publication: 2021 May 01.
DOI:	10.1016/j.ijid.2021.04.086
Abstrakt:	Objectives: A retrospective study was conducted to identify the prevalence of COVID-19 through serology and RT-PCR in children, adolescents and adults. A database of the COVID-19 Tracking Program in school children was used. Methods: The data comprised sociodemographic and clinical variables, results of serological tests (IgM and IgG), and real-time-polymerase chain reaction (RT-PCR) results of IgM-positive individuals. The statistical analysis was performed with a 5% significance level. Results: Among 423 children, 107 (25.3%) exhibited seroprevalence with IgG, IgM or IgG/IgM; among 854 adolescents, 250 (29.2%) had positive serology; and among 282 adults, 59 (20.9%) were positive. The frequency of positivity on RT-PCR for SARS-CoV-2 was 3.5%, 3.6% and 6.0% in children, adolescents and adults, respectively. Children had a lower incidence of symptoms than adolescents (p = 0.001) and adults (p = 0.003); the most frequent were fever, ageusia, anosmia, headache, dry cough, sore throat, muscle pain, runny nose, dyspnoea, and diarrhoea. Conclusions: The prevalence rate for all groups was 26.7% in serology and 4.04% in RT-PCR. Children had lower rates of IgM and fewer symptoms compared with adolescents and adults. The data suggest the potential for transmissibility in all age groups. (Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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