| Autor: |
Torres-Avendaño JI; Posgrado en Ciencias Biológicas, Facultad de Biología, Universidad Autónoma de Sinaloa, Culiacán, México., Apodaca-Medina AI; Posgrado en Ciencias Biomédicas, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Culiacán, México., Castillo-Ureta H; Posgrado en Ciencias Biológicas, Facultad de Biología, Universidad Autónoma de Sinaloa, Culiacán, México., Rendón-Maldonado JG; Posgrado en Ciencias Biomédicas, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Culiacán, México., Torres-Montoya EH; Posgrado en Ciencias Biológicas, Facultad de Biología, Universidad Autónoma de Sinaloa, Culiacán, México., Cota-Medina A; Posgrado en Ciencias Biomédicas, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Culiacán, México., Ríos-Tostado JJ; Posgrado en Ciencias Biológicas, Facultad de Biología, Universidad Autónoma de Sinaloa, Culiacán, México., Zazueta-Moreno JM; Posgrado en Ciencias Biológicas, Facultad de Biología, Universidad Autónoma de Sinaloa, Culiacán, México. |
| Abstrakt: |
Dengue virus (DENV) is transmitted to humans by the bite of the vector Aedes aegypti . Several researchers have suggested that the mechanism of vertical transmission of DENV in the vector is a key aspect for the prevalence of the virus in the environment and the potentiation of epidemic outbreaks of the disease. In this context and as part of an integrated study of DENV serotypes in mosquitoes of urban areas in Sinaloa, Mexico, the presence of DENV-4 in larval stages of Ae. aegypti was evaluated to demonstrate the vertical transmission of this serotype. In total, 672 larvae of Ae. aegypti were collected in 16 sectors and were grouped into 36 pools, of which 41.66% (15/36 pools) tested positive for DENV-4, with a minimum infection rate = 22.32. The analysis of the obtained sequences showed a 98% similarity to the DENV-4 with sequences previously reported in GenBank. These results show that Ae. aegypti acts as a natural reservoir for DENV-4 in this region. |
