Platelet-Lymphocyte ratio is a predictor for the development of no-reflow phenomenon in patients with ST-segment elevation myocardial infarction after thrombus aspiration.

Autor: Şenöz O; Department of Cardiology, Bakırcay University Cigli Training and Research Hospital, Izmir, Turkey., Emren SV; Department of Cardiology, Katip Çelebi University Faculty of Medicine, Izmir, Turkey., Erseçgin A; Department of Cardiology, Bakırcay University Cigli Training and Research Hospital, Izmir, Turkey., Yapan Emren Z; Department of Cardiology, Bakırcay University Cigli Training and Research Hospital, Izmir, Turkey., Gül İ; Department of Cardiology, Tepecik Training and Research Hospital, Izmir, Turkey.
Jazyk: angličtina
Zdroj: Journal of clinical laboratory analysis [J Clin Lab Anal] 2021 Jun; Vol. 35 (6), pp. e23795. Date of Electronic Publication: 2021 May 04.
DOI: 10.1002/jcla.23795
Abstrakt: Backround: We aimed to evaluate the utility of the preprocedural platelet-lymphocyte ratio (PLR) for predicting the no-reflow phenomenon after thrombus aspiration during percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI).
Method: We retrospectively analyzed postprocedural thrombolysis in myocardial infarction (TIMI) flow grades and myocardial blush grades (MBG) of 247 patients who underwent a PCI procedure with thrombus aspiration.We divided these patients into two groups according to whether they had no-reflow (TIMI < 3, MBG < 2) or not (TIMI 3, MBG ≥ 2).
Results: No-reflow developed in 43 (17%) patients.Preprocedural PLR was significantly higher in the no-reflow group (183.76 ± 56.65 vs 118.32 ± 50.42 p < 0.001).Independent predictors of no-reflow were as follows: higher preprocedural platelet-lymphocyte ratio (PLR) (OR = 1.018; 95% CI = 1.004, 1.033; p = 0.013),mean corpuscular volume (MCV) (OR = 1.118; 95% CI = 1.024, 1.220; p = 0.012) and SYNTAX Score-2 (OR = 1.073; 95% CI = 1.005, 1.146; p = 0.036). PLR of 144 had 79% sensitivity and 75% specificity for the prediction of no-reflow.
Conclusion: PLR is a reliable predictor for no-reflow in STEMI patients undergoing thrombus aspiration.
(© 2021 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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